770732-16-6

Basic information

• Product Name: {(S)-1-[(1S,2R,3S)-1-(5-Cyclohexyl-pentyl)-2,3-dihydroxy-5-methyl-hexylcarbamoyl]-but-3-enyl}-carbamic acid tert-butyl ester
• Synonyms: {(S)-1-[(1S,2R,3S)-1-(5-Cyclohexyl-pentyl)-2,3-dihydroxy-5-methyl-hexylcarbamoyl]-but-3-enyl}-carbamic acid tert-butyl ester
• CAS NO: 770732-16-6
• Molecular Weight: 496.731
• Mol File: 770732-16-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(S)-1-[(1S,2R,3S)-1-(5-Cyclohexyl-pentyl)-2,3-dihydroxy-5-methyl-hexylcarbamoyl]-but-3-enyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-1-[(1S,2R,3S)-1-(5-Cyclohexyl-pentyl)-2,3-dihydroxy-5-methyl-hexylcarbamoyl]-but-3-enyl}-carbamic acid tert-butyl ester(770732-16-6)
• EPA Substance Registry System: {(S)-1-[(1S,2R,3S)-1-(5-Cyclohexyl-pentyl)-2,3-dihydroxy-5-methyl-hexylcarbamoyl]-but-3-enyl}-carbamic acid tert-butyl ester(770732-16-6)

Safety Data

• Hazardous Substances Data: 770732-16-6(Hazardous Substances Data)

Upstream product

• 90600-20-7 (2S)-2-[(tert-butoxycarbonyl)amino]pent-4-enoic acid 
• 167113-52-2 <4S-(4R*,5S*,6R*)>-6-amino-11-cyclohexyl-2-methylundecane-4,5-diol 
• 769954-38-3 [(1S,2R,3S)-1-(5-Cyclohexyl-pentyl)-2,3-dihydroxy-5-methyl-hexyl]-carbamic acid tert-butyl ester 

Downstream Products

• 771489-11-3 (S)-2-Amino-pent-4-enoic acid [(1S,2R,3S)-1-(5-cyclohexyl-pentyl)-2,3-dihydroxy-5-methyl-hexyl]-amide 

Relevant articles and documents

Design and synthesis of renin inhibitors: Incorporation of transition- state isostere side chains that span from the S1 to the S3 binding pockets and examination of P3-modified renin inhibitors

A series of renin inhibitors were designed to examine the topography of the contiguous binding pocket of renin that is normally occupied by the P1 and P3 side chains. Molecular modeling suggested that extending the P1 hydrophobic side chain into the adjac