7714-33-2Relevant articles and documents
Insertion of alkynes into diterpenoid chromium aminocarbenes: Synthesis of ring-C aromatic steroidal analogues
Woodgate, Paul D.,Sutherland, Hamish S.,Rickard, Clifton E.F.
, p. 206 - 220 (2001)
The insertion of alkyl- or aryl-substituted alkynes into chromium aminocarbenes derived from podocarpic acid gives good to excellent yields of cyclopentaannulated products. The presence of a heteroatom bonded directly to the alkyne lowers the yield of the indanones. Although no steroidal derivatives could be isolated from the use of acetylene or its synthons, the electron-deficient alkyne ethyl 4,4-dimethylpentyn-2-oate gave a good yield, as did ethynylferrocene. Novel diterpenoid ferrocenyl quinones were synthesised by reacting diterpenoid chromium alkoxycarbenes with ethynylferrocene.
One-pot synthesis of alkynylthiocyanates by phase-transfer reagent
Li, Ming,Song, Wangze,Dong, Kun,Zheng, Yubin
supporting information, (2019/12/25)
Thiocyano-group widely exist in natural products and drug structures. A novel one-pot synthesis of alkynylthiocyanates from terminal alkynes, [hydroxy(tosyloxy)iodo]benzene and potassium thiocyanate by phase-transfer reagent involving the hypervalent iodine intermediates in transition metal-free conditions was developed. The internal alkynylthiocyanates could be used to synthesize some important compounds such as 5-thiocyanato-1,2,3-triazoles and (Z)-α-thiocyanato-vinyl trifluoromethanesulfonate.
Synthesis of Alkynyl Sulfides by Copper-Catalyzed Thiolation of Terminal Alkynes Using Thiosulfonates
Kanemoto, Kazuya,Yoshida, Suguru,Hosoya, Takamitsu
supporting information, p. 3172 - 3177 (2019/05/10)
A mild and odorless copper-catalyzed thiolation of terminal alkynes with thiosulfonates is described. The broad substrate scope provides convenient access to a wide variety of sulfur-containing heterocycles. In particular, divergent benzoheteroles are efficiently prepared in a simple manner by thiolation of ethynylbenzenes bearing ortho-nucleophilic functional groups followed by iodocyclization.
