771581-60-3

Basic information

• Product Name: 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZYLAMINE
• Synonyms: 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZYLAMINE
• CAS NO: 771581-60-3
• Molecular Formula: C8H7ClF3NO
• Molecular Weight: 225.598
• Mol File: 771581-60-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZYLAMINE(771581-60-3)
• EPA Substance Registry System: 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZYLAMINE(771581-60-3)

Safety Data

• Hazardous Substances Data: 771581-60-3(Hazardous Substances Data)

Upstream product

• 129604-26-8 3-chloro-4-(trifluoromethoxy)benzonitrile 
• 261763-18-2 4-(bromomethyl)-2-chlorophenyl trifluoromethyl ether 

Downstream Products

• 1219687-06-5 N-[3-chloro-4-(trifluoromethoxy)benzyl]-3-fluoro-4-[(1,3-thiazol-2-ylamino)sulfonyl]benzamide 

Relevant articles and documents

The discovery of a potent Nav1.3 inhibitor with good oral pharmacokinetics

In this article, we describe the discovery of an aryl ether series of potent and selective Nav1.3 inhibitors. Based on structural analogy to a similar series of compounds we have previously shown bind to the domain IV voltage sensor region of Nav channels, we propose this series binds in the same location. We describe the development of this series from a published starting point, highlighting key selectivity and potency data, and several studies designed to validate Nav1.3 as a target for pain.

HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of GPR119 for the treatment or prevention of metabolic, cardiovascular, and metabolic diseases.