77180-90-6

Basic information

• Product Name: 5-FLUORO-1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL
• Synonyms: 5-FLUORO-1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL
• CAS NO: 77180-90-6
• Molecular Formula: C₃₀H₂₃FN₂O₉
• Molecular Weight: 574.515
• Mol File: 77180-90-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-FLUORO-1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-FLUORO-1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL(77180-90-6)
• EPA Substance Registry System: 5-FLUORO-1-(2'', 3'', 5''-TRI-O-BENZOYL-β-L-RIBOFURANOSYL)URACIL(77180-90-6)

Safety Data

• Hazardous Substances Data: 77180-90-6(Hazardous Substances Data)

Upstream product

• 1748-04-5 (2S,3S,4S,5S)-2-((benzoyloxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate 
• 3080-30-6 1-O-acetyl-2,3,5-tri-O-benzoyl-β-L-ribofuranose 
• 17242-85-2 5-fluoro-2,4-bis(trimethylsilyloxy)pyrimidine 

Downstream Products

• 77210-26-5 1-(3'-O-benzyl-β-L-ribofuranosyl)-5-fluorouracil 
• 725257-84-1 C₃₀H₂₃FN₂O₈S 

Relevant articles and documents

Stereospecific synthesis and biological evaluations of β-L-pentofuranonucleoside derivatives of 5-fluorouracil and 5-fluorocytosine

In the search for new chemotherapeutic agents, we have focused our work on the synthesis and the study of several unnatural β-L-nucleoside analogues. In this paper, we report on the synthesis of β-L-pentofuranonucleosides (and their 2′-deoxy derivatives) of 5-fluorouracil and their inhibitory effects on the proliferation of several murine and human tumor cells. The corresponding 5-fluorocytosine derivatives were also synthesized and their anti-HIV and anti-HBV activities have been evaluated.

Preparation, antibacterial effects and enzymatic degradation of 5-fluorouracil nucleosides

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