77196-48-6

Basic information

• Product Name: 4,5-Dioxo-1-p-tolyl-cyclopentane-1,3-dicarboxylic acid diethyl ester
• Synonyms: 4,5-Dioxo-1-p-tolyl-cyclopentane-1,3-dicarboxylic acid diethyl ester
• CAS NO: 77196-48-6
• Molecular Weight: 332.353
• Mol File: 77196-48-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,5-Dioxo-1-p-tolyl-cyclopentane-1,3-dicarboxylic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Dioxo-1-p-tolyl-cyclopentane-1,3-dicarboxylic acid diethyl ester(77196-48-6)
• EPA Substance Registry System: 4,5-Dioxo-1-p-tolyl-cyclopentane-1,3-dicarboxylic acid diethyl ester(77196-48-6)

Safety Data

• Hazardous Substances Data: 77196-48-6(Hazardous Substances Data)

Upstream product

• 10088-87-6 4,5-dioxo-cyclopentane-1,3-dicarboxylic acid diethyl ester 
• 6293-68-1 bis(4-methylphenyl)iodonium bromide 

Downstream Products

• 343779-02-2 2,5-dimethyl-2-p-tolyl-2-cyclopentanone 
• 74285-43-1 5-methyl-2-p-tolyl-2-cyclopentenone 
• 77196-49-7 2-methoxy-3-p-tolyl-2-cyclopentenone 
• 77183-98-3 2,5-dimethyl-2-p-tolyl-2-cyclopentenone 
• 77183-97-2 2-methyl-5-p-tolyl-2-cyclopentenone 

Relevant articles and documents

Synthesis of 2-Hydroxy-3-p-tolyl-2-cyclopentenone and Its Application to Isolaurene

2-Hydroxy-3-p-tolyl-2-cyclopentenone (7), a potential starting material for synthesis of isolaurene (1), was prepared by photolysis of 2-p-toluenesulfonyloxy-2-cyclopentenone (6).Conversion of 7 into 2,5-dimethyl-2-p-tolyl-cyclopentanone (14) was carried out as follows.Methylation of 7 with methyl iodide gave 2-methoxy-3-p-tolyl-2-cyclopentanone (9), and the treatment of (9) with methyl magnesium iodide afforded 2-methyl-5-p-tolyl-2-cyclopentenone (11).This compound was allowed to react with methyl iodide in the presence of sodium methoxide to yield 2,5-dimethyl-2-p-tolyl-4-cyclopentenone (13), the hydrogenation of which over palladium charcoal gave 14.