77199-12-3

Basic information

• Product Name: 3-Bromoquinolizinium bromide
• Synonyms: 3-Bromoquinolizinium bromide
• CAS NO: 77199-12-3
• Molecular Formula: Br*C₉H₇BrN
• Molecular Weight: 288.96658
• Mol File: 77199-12-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Bromoquinolizinium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromoquinolizinium bromide(77199-12-3)
• EPA Substance Registry System: 3-Bromoquinolizinium bromide(77199-12-3)

Safety Data

• Hazardous Substances Data: 77199-12-3(Hazardous Substances Data)

Upstream product

• 3430-13-5 5-bromo-2-methylpyridine 
• 30766-11-1 5-bromoisonicotinic acid 
• 77199-09-8 5-bromo-pyridine-2-carboxylic acid ethyl ester 
• 77199-10-1 α-<5-bromopicoloyl>-γ-butyrolactone 

Downstream Products

• 86818-46-4 1-acetylamino-4-<2-pyridyl>butane 

Relevant articles and documents

Palladium-mediated functionalization of heteroaromatic cations: Comparative study on quinolizinium cations

An efficient palladium-catalyzed cross-coupling reaction on heteroaromatic cations is described. A comparative study of the Stille and Suzuki reactions shows that only the Stille reaction is able to produce an efficient C-C bond formation between any of the four isomeric bromoquinolizinium bromides and a variety of stannanes. In the presence of the catalysts Pd(PPh3)4 or Pd2(dba)3P(o-Tol)3, vinyl, ethynyl, aryl, and heteroaryl groups are successfully incorporated into the quinolizinium system in satisfactory yields under mild reaction conditions. This procedure represents a marked improvement on the functionalization of this class of heteroaromatic cation.