772-23-6

Basic information

• Product Name: Benzene, 2,4-dichloro-1-(difluoromethoxy)-
• CAS NO: 772-23-6
• Molecular Formula: C7H4Cl2F2O
• Molecular Weight: 213.011
• Mol File: 772-23-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 2,4-dichloro-1-(difluoromethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2,4-dichloro-1-(difluoromethoxy)-(772-23-6)
• EPA Substance Registry System: Benzene, 2,4-dichloro-1-(difluoromethoxy)-(772-23-6)

Safety Data

• Hazardous Substances Data: 772-23-6(Hazardous Substances Data)

Upstream product

• 401-27-4 (+/-)-(2,4-dichloro-phenoxy)-fluoro-acetic acid ethyl ester 
• 398-82-3 2-fluoro-2-(2,4-dichlorophenoxy)acetic acid 
• 403496-62-8 p-chlorophenyl chlorodifluoromethyl sulfone 
• 120-83-2 2,4-dichlorophenol 
• 930836-30-9 (chlorodifluoromethylsulfonyl)benzene 
• 384-67-8 2-chloro-2,2-difluoroacetophenone 

Relevant articles and documents

Xenon Difluoride Mediated Fluorodecarboxylations for the Syntheses of Di- and Trifluoromethoxyarenes

XeF2 is demonstrated to be a more proficient fluorine-transfer reagent than either NFSI or Selectfluor in fluorodecarboxylations of both mono- and difluoroaryloxy acetic acid derivatives. This method efficiently converts a wide range of neutral and electron-poor substrates to afford the desired di- and trifluoromethyl aryl ethers in good to excellent yields. The purifications are facile, and the reaction times are less than 5 min, which makes these fluorodecarboxylations promising for future PET-imaging applications.

Chlorodifluoromethyl phenyl sulfone: A novel non-ozone-depleting substance-based difluorocarbene reagent for O- and N-difluoromethylations

Chlorodifluoromethyl phenyl sulfone, a previously unknown compound that can be readily prepared from non-ODS-based precursors, was found to act as a robust difluorocarbene reagent for O- and N-difluoromethylations. The Royal Society of Chemistry.