77227-81-7

Basic information

• Product Name: 3,5-Dichloro-4-fluorobenzotrifluoride
• Synonyms: 1,3-DICHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)BENZENE;3,5-DICHLORO-ALPHA,ALPHA,ALPHA-4-TETRAFLUOROTOLUENE;3,5-dichloro-4-fluoro-alpha,alpha,alpha-trifluorotoluene;3,5-DICHLORO-4-FLUOROBENZOTRIFLUORIDE;Benzene, 1,3-dichloro-2-fluoro-5-(trifluoromethyl)-;3,5-Dichloro-4-fluorobenzotrifluoride 98%;3,5-Dichloro-4-fluorobenzotrifluoride98%;3,5-Dichloro-4-fluoronitrobezene
• CAS NO: 77227-81-7
• Molecular Formula: C₇H₂Cl₂F₄
• Molecular Weight: 232.99
• EINECS: -0
• Product Categories: Aryl;C7;Halogenated Hydrocarbons;Aryl Fluorinated Building Blocks;Building Blocks;Chemical Synthesis;Fluorinated Building Blocks;Halogenated Hydrocarbons;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks
• Mol File: 77227-81-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 166-168 °C(lit.)
• Flash Point: 164 °F
• Appearance: clear light yellow liquid
• Density: 1.555 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.54mmHg at 25°C
• Refractive Index: n20/D 1.462(lit.)
• BRN: 6199573
• CAS DataBase Reference: 3,5-Dichloro-4-fluorobenzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dichloro-4-fluorobenzotrifluoride(77227-81-7)
• EPA Substance Registry System: 3,5-Dichloro-4-fluorobenzotrifluoride(77227-81-7)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-41
• Safety Statements: 26-36
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 77227-81-7(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR LIGHT YELLOW LIQUID

Uses

3,5-Dichloro-4-fluorobenzotrifluoride may be used for the synthesis of 3-[4-[1-(2,6-dichloro-3-iodo-4-trifluoromethylphenyl)-5-iodopyrazolo]]-3-(trifluoromethyl)diazirine.

General Description

3,5-Dichloro-4-fluorobenzotrifluoride is an aryl fluorinated building block.

InChI:InChI=1/C7H2Cl2F4/c8-4-2-6(10)5(9)1-3(4)7(11,12)13/h1-2H

Upstream product

• 50594-82-6 1-trifluoromethyl-3,4,5-trichlorobenzene 
• 13755-29-8 sodium tetrafluoroborate 
• 24279-39-8 2,6-dichloro-4-(trifluoromethyl)aniline 

Downstream Products

• 98191-30-1 3,5-dichloro-4-fluorobenzoic acid 
• 452098-03-2 3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole 
• 452098-98-5 N-allyl-3-(2,6-dichloro-4-trifluoromethylphenyloxy)-5-methylpyrazole-1-carboxamide 
• 249893-20-7 3-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-1,2,4-triazole 
• 129931-45-9 3-chloro-2-fluoro-5-(trifluoromethyl)benzoic acid 
• 133306-97-5 1-(2,6-dichloro-4-trifluoromethylphenyl)-5-amino-4-trifluoromethylpyrimidin-6-one 
• 115551-51-4 4-ethoxy carbonyl-1-(2,6-dichloro-4-trifluoromethyl-phenyl)-2-pyridone 

Relevant articles and documents

PROCESS FOR PREPARING 2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE USING MIXTURES OF DICHLORO-FLUORO-TRIFLUOROMETHYLBENZENES

This invention relates to a process for preparing 2,6-dichloro-4- (trifluoromethyl)phenylhydrazine of the formula (I) wherein a mixture comprising 1,3-dichloro-2-fluoro-5-trifluoromethylbenzene and 1,2-dichloro-3-fluoro-5-trifluoromethylbenzene is reacted with a hydrazine source selected from hydrazine, hydrazine hydrate or acid addition salts of hydrazine, optionally in the presence of at least one organic solvent.

Substituted diphenyl ethers

A compound of the formula: STR1 and salts and esters thereof, useful as intermediates for the preparation of compounds of the formula STR2 wherein R1 is an alkyl group optionally substituted by one or more fluorine atoms or by an optionally substituted phenyl group R2 is No2 or Cl and R6 is a hydrogen atom or an alkyl group of 1 to 4 carbon atoms.