772318-01-1

Basic information

• Product Name: 7-({methanesulfonyl-[4-(piperidin-4-yloxy)-phenyl]-amino}-methyl)-naphthalene-2-carboxamidine
• CAS NO: 772318-01-1
• Molecular Weight: 452.577
• Mol File: 772318-01-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-({methanesulfonyl-[4-(piperidin-4-yloxy)-phenyl]-amino}-methyl)-naphthalene-2-carboxamidine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-({methanesulfonyl-[4-(piperidin-4-yloxy)-phenyl]-amino}-methyl)-naphthalene-2-carboxamidine(772318-01-1)
• EPA Substance Registry System: 7-({methanesulfonyl-[4-(piperidin-4-yloxy)-phenyl]-amino}-methyl)-naphthalene-2-carboxamidine(772318-01-1)

Safety Data

• Hazardous Substances Data: 772318-01-1(Hazardous Substances Data)

Upstream product

• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 179756-21-9 N-{4-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]phenyl}-N-[(7-cyano-2-naphthyl)methyl]methanesulfonamide 
• 454437-33-3 N-{4-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]phenyl}methanesulfonamide 
• 138227-62-0 tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate 
• 138227-63-1 tert-butyl 4-(4-aminophenoxy)piperidine-1-carboxylate 
• 188616-78-6 7-cyanonaphthalen-2-yl trifluoromethanesulfonate 
• 90381-43-4 7-methoxynaphthalene-2-carbonitrile 
• 135653-94-0 7-methoxy-2-trifluoromethanesulfonyloxynaphthalene 
• 350-46-9 4-Fluoronitrobenzene 
• 135942-98-2 7-(bromomethyl)naphthalene-2-carbonitrile 
• 130200-58-7 7-hydroxynaphthalene-2-carbonitrile 
• 5060-82-2 7-methoxy-2-naphthol 
• 38879-96-8 7-methyl-2-naphthalene carbonitrile 
• 454436-34-1 4-{4-[(7-carbamimidoyl-naphthalen-2-ylmethyl)-methanesulfonyl-amino]-phenoxy}-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors

A series of benzoxazinone derivatives was designed and synthesized as factor Xa inhibitors. We demonstrated that the naphthyl moiety in the aniline-based compounds 1 and 2 can be replaced with benzene-fused heterobicycles and biaryls to give factor Xa inh