77252-87-0 Usage
Description
Propranolol Impurity, specifically N-Formylpropranolol, is an impurity of propranolol (CAS: 525-66-6), a medication with various therapeutic applications. It is characterized by its role as a β-adrenergic blocker, which contributes to its effectiveness in treating hypertension, angina, and arrhythmias (class II).
Uses
Used in Pharmaceutical Preparations:
Propranolol Impurity is used as an ingredient in the preparation of calcium blockers and β-blockers, which are essential in managing cardiovascular conditions such as high blood pressure, angina, and irregular heartbeats.
Used in Organic Chemistry:
In the field of organic chemistry, Propranolol Impurity serves as a starting material for the synthesis of Indole and naphthalene derivatives. These compounds have potential applications in various chemical and pharmaceutical processes, making the impurity a valuable component in the development of new compounds and drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 77252-87-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,2,5 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77252-87:
(7*7)+(6*7)+(5*2)+(4*5)+(3*2)+(2*8)+(1*7)=150
150 % 10 = 0
So 77252-87-0 is a valid CAS Registry Number.
77252-87-0Relevant articles and documents
A novel type of N-formylation and related reactions of amines via cyanides and esters as formylating agents
Bao, Kai,Zhang, Weige,Bu, Xiujuan,Song, Zhichun,Zhang, Liang,Cheng, Maosheng
supporting information; experimental part, p. 5429 - 5431 (2009/03/11)
A novel N-formylation and related reactions proceed from cyanides promoted by esters. The Royal Society of Chemistry.
Approaches to mutual prodrugs: Calcium-β-blockers
Nudelman,Kelner
, p. 907 - 909 (2007/10/02)
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