773095-61-7

Basic information

• Product Name: 2-(2-bromo-4-methylphenyl)-1,3-dioxolane
• Synonyms: 2-(2-bromo-4-methylphenyl)-1,3-dioxolane
• CAS NO: 773095-61-7
• Molecular Weight: 243.1
• Mol File: 773095-61-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2-(2-bromo-4-methylphenyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromo-4-methylphenyl)-1,3-dioxolane(773095-61-7)
• EPA Substance Registry System: 2-(2-bromo-4-methylphenyl)-1,3-dioxolane(773095-61-7)

Safety Data

• Hazardous Substances Data: 773095-61-7(Hazardous Substances Data)

Upstream product

• 824-54-4 2-bromo-4-methylbenzaldehyde 
• 107-21-1 ethylene glycol 

Downstream Products

• 1292281-56-1 2-(1,3-dioxolan-2-yl)-5-methylbenzaldehyde 
• 1292281-31-2 C₁₈H₂₂O₄S₂ 
• 1292281-32-3 C₁₆H₁₈O₄S₂ 
• 1292281-59-4 C₁₈H₂₂O₆ 
• 1292281-60-7 C₁₆H₁₈O₆ 
• 1619256-51-7 C₂₁H₂₂N₂ 
• 1619256-34-6 4-methyl-2-(2-methylallyl)benzaldehyde 
• 1619256-33-5 2-(4-methyl-2-(2-methylallyl)phenyl)-1,3-dioxolane 

Relevant articles and documents

Cobalt-Catalyzed Chemoselective Transfer Hydrogenative Cyclization Cascade of Enone-Tethered Aldehydes

The ligand-free Co-catalyzed chemoselective reductive cyclization cascade of enone-tethered aldehydes with i-PrOH as the environmentally benign hydrogen surrogate is developed by this study. Mechanistic studies disclosed that such a protocol is initiated

Efficient synthesis of dibenzazepine lactams via a sequential Pd-catalyzed amination and aldol condensation reaction

A simple and efficient reaction was developed for the synthesis of dibenzazepine lactam derivatives. The core 7-membered azepine ring was formed by a stepwise sequence involving a palladium-catalyzed amination and an aldol condensation.

Catalytic Dibenzocyclooctene Synthesis via Cobalt(III)–Carbene Radical and ortho-Quinodimethane Intermediates

The metalloradical activation of ortho-benzallylaryl N-tosyl hydrazones with [Co(TPP)] (TPP=tetraphenylporphyrin) as the catalyst enabled the controlled exploitation of the single-electron reactivity of the redox non-innocent carbene intermediate. This method offers a novel route to prepare eight-membered rings, using base metal catalysis to construct a series of unique dibenzocyclooctenes through selective Ccarbene?Caryl cyclization. The desired eight-membered-ring products were obtained in good to excellent yields. A large variety of aromatic substituents are tolerated. The proposed reaction mechanism involves intramolecular hydrogen atom transfer (HAT) to CoIII–carbene radical intermediates followed by dissociation of an ortho-quinodimethane that undergoes 8π cyclization. The mechanism is supported by DFT calculations, and the presence of radical-type intermediates was confirmed by trapping experiments.