773095-63-9

Basic information

• Product Name: methyl 4-(1,3-dioxolan-2-yl)-3-nitrobenzoate
• Synonyms: methyl 4-(1,3-dioxolan-2-yl)-3-nitrobenzoate
• CAS NO: 773095-63-9
• Molecular Weight: 253.211
• Mol File: 773095-63-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 4-(1,3-dioxolan-2-yl)-3-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(1,3-dioxolan-2-yl)-3-nitrobenzoate(773095-63-9)
• EPA Substance Registry System: methyl 4-(1,3-dioxolan-2-yl)-3-nitrobenzoate(773095-63-9)

Safety Data

• Hazardous Substances Data: 773095-63-9(Hazardous Substances Data)

Upstream product

• 107-21-1 ethylene glycol 
• 153813-69-5 methyl 4-formyl-3-nitrobenzoate 

Downstream Products

• 1422387-39-0 methyl N-(4-(6-((1S)-1-((tert-butoxycarbonyl)amino)but-3-en-1-yl)-2-oxo-1,2-dihydropyridin-4-yl)-3-(pent-4-enoylamino)phenyl)carbamate 
• 1422387-37-8 methyl N-(4-(6-((1S)-1-((tert-butoxycarbonyl)amino)but-3-en-1-yl)-2-oxo-1,2-dihydropyridin-4-yl)-3-((2-methylbut-3-enoyl)amino)phenyl)carbamate 
• 1422388-52-0 methyl N-(3-amino-4-(6-((1S)-1-((tert-butoxycarbonyl)amino)but-3-en-1-yl)-2-oxo-1,2-dihydropyridin-4-yl)phenyl)carbamate 
• 1422388-77-9 C₂₂H₂₈N₄O₅ 
• 1422511-37-2 C₁₀H₈N₄O₅ 
• 1422387-83-4 methyl N-(4-{2-[(1S)-1-{[(tert-butoxy)carbonyl]amino}but-3-en-1-yl]-6-methoxypyridin-4-yl}-3-(2-methylbut-3-enamido)phenyl)carbamate 
• 1422387-82-3 methyl N-(3-amino-4-{2-[(1S)-1-{[(tert-butoxy)carbonyl]amino}but-3-en-1-yl]-6-methoxypyridin-4-yl}phenyl)carbamate 
• 1422387-81-2 methyl N-(4-{2-[(1S)-1-{[(tert-butoxy)carbonyl]amino}but-3-en-1-yl]-6-methoxypyridin-4-yl}-3-nitrophenyl)carbamate 
• 1422387-35-6 methyl N-(4-((1E,4S)-4-((tert-butoxycarbonyl)amino)-3-oxohepta-1,6-dien-1-yl)-3-nitrophenyl)carbamate 
• 1422387-34-5 methyl N-(4-formyl-3-nitrophenyl)carbamate 
• 1422387-33-4 methyl N-(4-(1,3-dioxolan-2-yl)-3-nitrophenyl)carbamate 
• 1422387-32-3 4-(1,3-dioxolan-2-yl)-3-nitrobenzoic acid 

Relevant articles and documents

The second factor as inhibitor XIA pyridonecarboxylic dihydropyridines P1

The present invention provides compounds of Formula (X):(Formula (X), or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.

NOVEL MACROCYCLES AS FACTOR XIA INHIBITORS

The present invention provides compounds of Formula (Ia): or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.