7733-02-0 Usage
Description
Zinc sulfate, also known as white vitriol, is a white crystalline water-soluble compound with the chemical formula ZnSO4. It occurs in nature as the mineral zincosite and is available in various hydrate forms, such as heptahydrate (ZnSO4·7H2O) and hexahydrate (ZnSO4·6H2O). It is easily soluble in water and has a convergence property, with its aqueous solution being acidic. Zinc sulfate is noncombustible and poses a primary hazard to the environment.
Uses
Used in Agriculture:
Zinc sulfate is used as a fertilizer to overcome zinc deficiency in plants. It is sprayed on the foliage as a water solution or added directly to the soil.
Used in Animal Nutrition:
Zinc sulfate is used as a feed supplement for animal nutrition upon zinc deficiency and as an additive in animal feeds.
Used in Textile Industry:
Zinc sulfate is used as a mordant in calico-printing and as a component in media for in vitro hyphal growth assays.
Used in Chemical Industry:
Zinc sulfate is used in the production of rayon, as a component of spinning baths for the production of synthetic silks, and in the preparation of many zinc compounds.
Used in Electroplating:
Zinc sulfate is used in zinc plating and as a mordant.
Used in Pharmaceutical Industry:
Zinc sulfate is used as an emetic agent, astringent, and in the preparation of electrolyte solutions for the electrolytic production of zinc metal.
Used in Wood and Leather Preservation:
Zinc sulfate is used as a preservative for wood and hides.
Used in Environmental Applications:
Zinc sulfate is used as a froth flotation agent and as an accelerating agent in dental impression material.
Used in Laboratory Applications:
Zinc sulfate solution is used as a supplement in the media along with isopropyl β-D-1-thiogalactopyranoside (IPTG) for expressing zinc-containing proteins.
Used in Medical Applications:
Zinc sulfate is used in conjunction with barium hydroxide to deproteinize whole blood, plasma, or serum samples for subsequent analysis of glucose by the Somogi-Nelson method.
Industrial uses:
Zinc sulfate is used in the production of carbamate fungicides, zinc plating baths, and ophthalmic solutions. It is also used as an additive in the production of pigment lithopone, zinc barium, and other zinc compounds.
Indications
Convergence preservatives: as eye drops, can be used for the treatment of conjunctivitis, trachoma, nasal blepharitis and so on.
Oral stimulation of gastric mucosa can cause reflex vomiting. It can be used as emetic drug, now less used.
It can be used for the treatment of zinc deficiency: zinc is the ingredient of many important enzymes in vivo such as carbonic anhydrase and alkaline phosphatase, being an indispensable trace element in the human body. Supplementation of zinc can be used for treating zinc deficiency such as dwarfism, acral dermatitis and zinc deficiency caused by long-term vein nutritional deficiency and so on.
It can be used for the treatment of zinc deficiency related diseases: such as acne vulgaris, skin ulcers (venous, arterial, leprosy), psoriasis, seborrheic dermatitis, chronic eczema, oral ulcers, hair loss and smell taste disorders.
It can be used as mordant for printing and dyeing, wood preservative, bleaching agent for papermaking, also used in medicine, artificial fiber, electrolysis, electroplating, and pesticide as well as zinc salt production.
Production Methods
Zinc sulfate is produced as an intermediate in recovering zinc from mineral zinc blende, ZnS (see Zinc, Recovery). The mineral is roasted at about 1,000°C to form zinc oxide and sulfur dioxide which, on prolonged heating in excess air, converts to zinc sulfate:
2ZnS + 3O2 → 2ZnO + 2SO2
992 ZINC SULFATE2ZnO + 2SO2 + O2 → 2ZnSO4
In the zinc recovery process, roasted products are leached with sulfuric acid, whereupon zinc oxide is converted to sulfate.
ZnO + H2SO4 → ZnSO4 + H2O
Also, zinc sulfate can be prepared by reacting metallic zinc with dilute sulfuric acid followed by evaporation and crystallization:
Zn + H2SO4 → ZnSO4 + H2
Production Methods
Zinc sulfate is produced from side streams of electrolytic
zinc manufacture. The main source of secondary zinc for
zinc sulfate production is galvanizer residues. ZnSO4 is
available as the mono-, hexa- and heptahydrates with zinc
contents of 36%, 24%, and 22%, respectively.
Air & Water Reactions
Water soluble. Efflorescent in air. Aqueous solutions are acidic.
Reactivity Profile
Acidic salts, such as Zinc sulphate, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.
Health Hazard
Inhalation of dust causes irritation of nose and throat. Ingestion can cause irritation or corrosion of the alimentary tract. Contact with eyes or skin causes irritation.
Biochem/physiol Actions
Zinc sulfate?solution is as potent as formalin. This chemical is mainly used to treat footrot. It may also be used to treat acute bronchiolitis.
Safety Profile
Poison by ingestion,
intraperitoneal, subcutaneous, and
intravenous routes. Human systemic effects
by ingestion: acute pulmonary edema,
agranulocytosis, blood pressure decrease,
diarrhea and other gastrointestinal changes,
hypermotility, increased pulse rate without
blood pressure decrease, level changes for
metals other than Na/K/Fe/Ca/P/Cl,
microcytosis with or without anemia,
normocytic anemia. Experimental
teratogenic and reproductive effects.
Questionable carcinogen with experimental
tumorigenic data. Human mutation data
reported. An eye irritant. When heated to
decomposition it emits toxic fumes of SOx
and ZnO. See also SULFATES and ZINC
COMPOUNDS.
Check Digit Verification of cas no
The CAS Registry Mumber 7733-02-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,3 and 3 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7733-02:
(6*7)+(5*7)+(4*3)+(3*3)+(2*0)+(1*2)=100
100 % 10 = 0
So 7733-02-0 is a valid CAS Registry Number.
InChI:InChI=1/H2O4S.Zn/c1-5(2,3)4;/h(H2,1,2,3,4);/p-2
7733-02-0Relevant articles and documents
Jeffreys, C. E. P.,Swift, E. H.
, p. 3219 - 3228 (1932)
Joshi, N. K.,Devadatta, S. C.
, p. 130 - 138 (1938)
Crystallization and characterization of the compounds Gly·MSO 4·mH2O (M = Mg2+, Mn2+, Fe2+, Co2+, Ni2+, Zn2+; M = 0, 3, 5, 6)
Tepavitcharova,Rabadjieva,Havlí?ek,Němec,Vojtí?ek,Plocek,Koleva
, p. 113 - 121 (2012)
The equilibrium crystallization of complex compounds of the type Gly·MSO4·5H2O with a structure derived from those of the crystallized double salts MSO4·xH2O, where x = 6, 7 was predicted and proven in the systems Gly-MSO 4-H2O (M = Mg2+, Mn2+, Fe 2+, Co2+, Ni2+ and Zn2+). It was predicted that stable octahedral complexes [M(H2O)6] 2+ and trans-[M(H2O)4(O-gly)2] 2+, as well as [SO4]2- tetrahedra, which were the main building units of the crystallizing Gly·MSO4· 5H2O compounds (triclinic crystal system, space group P - 1), were predominating in these solutions. The vibrational spectra and the thermal behavior of the Gly·MSO4·5H2O compounds (M = Mg2+, Co2+, Zn2+) are in accord with the refined crystal structures. The cobalt compound displays antiferromagnetic behavior whereas the nickel and manganese compounds are ferromagnetic. In the manganese system where MnSO4·H2O (308 K) crystallizes, the only complex compound is the anhydrous Gly·MnSO 4 with a polymeric type structure (trans-[Mn(SO4) 4(O-gly)2]n2-). A new compound Gly·CoSO 4·3H2O was found in the cobalt system under unstable equilibrium conditions. Gly·CoSO4·3H 2O was proven to consist of two types of octahedra, trans-[Co(H 2O)4(O-gly)2]2+ and trans-[Co(H 2O)2(SO4)2(O-gly)2] 2-, forming a chain structure (monoclinic crystal system, space group P21/c).
Copeland, I. C.,Short, O. A.
, p. 3285 - 3291 (1940)
AQUEOUS COMPOSITION AND METHOD OF PRODUCING CHLORINE DIOXIDE USING AQUEOUS COMPOSITION
-
, (2018/07/15)
An aqueous composition includes an activator, a chlorite ion source, and water. The aqueous composition is alkaline. The aqueous composition produces chlorine dioxide upon contact with an acid. A method of producing chlorine dioxide includes contacting the aqueous composition with an acid.
METHOD OF PROMOTING WOUND HEALING
-
Page/Page column, (2015/03/16)
A method of establishing a therapeutic window of wound fluid nitric oxide (WFNO) in the wound of a mammal, the method including: obtaining a wound fluid sample from a mammal; analyzing the WFNO level; determining whether the WFNO is at or below a lower threshold level, or is at or above an upper threshold level; wherein the lower threshold level and upper threshold level define the therapeutic window of WFNO; and treating the mammal with a substance that alters the WFNO level such that the therapeutic window of WFNO in the wound is established.