77337-52-1

Basic information

• Product Name: LYSINE ACETYL-SALICYLATE
• Synonyms: LYSINE ACETYL-SALICYLATE;LYSINE ACETYLSALICYLIC ACID
• CAS NO: 77337-52-1
• Molecular Formula: C15H22N2O6
• Molecular Weight: 326.34
• Mol File: 77337-52-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: LYSINE ACETYL-SALICYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: LYSINE ACETYL-SALICYLATE(77337-52-1)
• EPA Substance Registry System: LYSINE ACETYL-SALICYLATE(77337-52-1)

Safety Data

• Hazardous Substances Data: 77337-52-1(Hazardous Substances Data)

Upstream product

• 56-87-1 L-lysine 
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Relevant articles and documents

IMPROVED SYNTHESIS OF LYSINE ACETYLSALICYLATE · GLYCINE PARTICLES

The invention relates to a method for the production of acetylsalicylic acid lysinate, optionally lysine acetylsalicylate · glycine, comprising the following steps: a) providing a solution of acetylsalicylic acid in ethanol; b) providing an aqueous solution of lysine; c) combining the solutions of step a) and b) to form a mixture; d) optionally stirring the mixture; e) adding acetone to the mixture; f) incubating the mixture, to allow the formation of a acetylsalicylic acid lysinate product; g) isolating the acetylsalicylic acid lysinate product; wherein acetylsalicylic acid is used in excess compared to lysine and wherein no seed crystals are added to the mixture; and optionally the following further steps: h) providing a recrystallized glycine; wherein the glycine has been recrystallized with the following steps: h1) dissolving glycine in water; h2) adding acetone to the glycine solution; h3) stirring the mixture until a precipitate is obtained; i) combining the recrystallized glycine of step h) with the acetylsalicylic acid lysinate product of step g) to obtain lysine acetylsalicylate · glycine (LASAG) particles.

Interactions of acetylsalicyclic acid and lysine in solution

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