77350-52-8

Basic information

• Product Name: N,N-diethyl-4-iodobenzamide
• Synonyms: N,N-diethyl-4-iodobenzamide
• CAS NO: 77350-52-8
• Molecular Formula: C₁₁H₁₄INO
• Molecular Weight: 303.13943
• Mol File: 77350-52-8.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,N-diethyl-4-iodobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-4-iodobenzamide(77350-52-8)
• EPA Substance Registry System: N,N-diethyl-4-iodobenzamide(77350-52-8)

Safety Data

• Hazardous Substances Data: 77350-52-8(Hazardous Substances Data)

Usage

General Description

N,N-diethyl-4-iodobenzamide is a chemical compound that belongs to the amide and benzene derivative classes. It contains a diethylamine group and an iodine atom attached to a benzene ring. N,N-diethyl-4-iodobenzamide is commonly used as a reagent in organic synthesis, specifically in the preparation of various pharmaceutical and agrochemical products. It can also be used as an intermediate in the manufacturing of dyes and other organic compounds. N,N-diethyl-4-iodobenzamide is known for its high reactivity and is often handled and stored with caution due to its potential hazards.

Upstream product

• 109-89-7 diethylamine 
• 1711-02-0 4-iodobenzoic acid chloride 
• 619-58-9 4-iodobenzoic acid 

Downstream Products

• 130447-19-7 N,N-Diethyl-4-furan-2-yl-benzamide 
• 130447-17-5 N,N-diethyl-4-(thiophen-2-yl)benzamide 
• 308110-26-1 N,N-diethyl-4-[hydroxy(5-isoquinolinyl)methyl]benzamide 
• 308110-38-5 N,N-diethyl-4-(hydroxy-quinolin-7-yl-methyl)-benzamide 
• 308110-39-6 N,N-diethyl-4-(hydroxy-quinolin-6-yl-methyl)-benzamide 
• 308110-32-9 4-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)(hydroxy)methyl]-N,N-diethylbenzamide 
• 209807-98-7 4-(4'-N',N'-diethylaminocarbonylbenzoyl)-N-tert-butoxycarbonylpiperidine 
• 308110-29-4 N,N-diethyl-4-[hydroxy[1-(phenylsulfonyl)-1H-indol-6-yl]methyl]benzamide 
• 193217-40-2 4-(α-hydroxy-α-(4-N-tert-butoxycarbonylpiperidinyl)benzyl)-N,N-diethylbenzamide 
• 209808-08-2 4-(α-hydroxy-α-(4-N-tert-butoxycarbonylpiperidinyl)-4-chlororobenzyl)-N,N-diethylbenzamide 
• 390366-08-2 4,4'-bis[(4-(N,N-diethylcarboxamido)phenyl)ethynyl]-2,2'-bipyridinyl 
• 390366-28-6 5,5'-bis[(4-(N,N-diethylcarboxamido)phenyl)ethynyl]-2,2'-bipyridinyl 
• 1696-17-9 N,N-diethylbenzamide 

Relevant articles and documents

Butenolide synthesis from functionalized cyclopropenones

A general method to synthesize substituted butenolides from hydroxymethylcyclopropenones is reported. Functionalized cyclopropenones undergo ring-opening reactions with catalytic amounts of phosphine, forming reactive ketene ylides. These intermediates can be trapped by pendant hydroxy groups to afford target butenolide scaffolds. The reaction proceeds efficiently in diverse solvents and with low catalyst loadings. Importantly, the cyclization is tolerant of a broad range of functional groups, yielding a variety of α- and γ-substituted butenolides.

SOLID FORMS OF 4-{(R)-(3-AMINOPHENYL)[4-(4-FLUOROBENZYL)-PIPERAZIN-1-YL]METHYL}-N,N-DIETHYLBENZAMIDE, COMPOSITIONS THEREOF, AND USES THEREWITH

Solid forms comprising salts of 4-{(R)-(3-aminophenyl)[4-(4-fluorobenzyl)piperazin-1- yl]methyl}-N,N-diethylbenzamide, compositions comprising the solid forms, methods of making the solid forms, and methods of their use for the treatment of various diseas

Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships

In the investigation of the structure-activity relationship of nonpeptide AT2 receptor agonists, a series of substituted benzamide analogues of the selective nonpeptide AT2 receptor agonist M024 have been synthesised. In a second ser