77379-03-4Relevant articles and documents
Hydrogen bond contribution to preferential solvation in SNAr reactions
Ormazabal-Toledo, Rodrigo,Santos, Jose G.,Rios, Paulina,Castro, Enrique A.,Campodonico, Paola R.,Contreras, Renato
, p. 5908 - 5915 (2013)
Preferential solvation in aromatic nucleophilic substitution reactions is discussed using a kinetic study complemented with quantum chemical calculations. The model system is the reaction of a series of secondary alicyclic amines toward phenyl 2,4,6-trinitrophenyl ether in aqueous ethanol mixtures of different compositions. From solvent effect studies, it is found that only piperidine is sensitive to solvation effects, a result that may be traced to the polarity of the solvent composition in the ethanol/water mixture, which points to a specific electrophilic solvation in the aqueous phase.
Kinetic and equilibrium studies of σ-adduct formation and nucleophilic substitution in the reactions of morpholine with 1,3,5-trinitrobenzene and some phenyl aryl ethers in dimethyl sulphoxide
Chamberlin, Rachel A.,Crampton, Michael R.,Robotham, Ian A.
, p. 152 - 158 (2007/10/03)
Reactions of morpholine in dimethyl sulphoxide at unsubstituted ring positions of 1,3,5-trinitrobenzene, and phenyl 2,4,6-trinitrophenyl ether, yield anionic σ-adducts via zwitterionic intermediates. Reactions at the 1-position of phenyl 2,4,6-trinitrophe
Kinetics of the Reactions of Phenyl 2,4,6-Trinitrophenyl Ether with Piperidine, n-Butylamine, Aniline, Benzylamine, and Morpholine in Benzene
Banjoko, Olayinka,Khalil-Ur-Rahman
, p. 1105 - 1108 (2007/10/02)
The kinetics of the reactions of phenyl 2,4,6-trinitrophenyl ether with piperidine, n-butylamine, benzylamine, and morpholine have been investigated as a function of the amine concentration in benzene and the results compared with that of aniline.Base-cat
