77461-97-3 Usage
Description
(2,5-dioxotetrahydrofuran-3-yl)acetyl chloride is a chemical compound with the molecular formula C8H11ClO4. It is a derivative of acetyl chloride, featuring a substituent group that contains a dioxotetrahydrofuran ring. (2,5-dioxotetrahydrofuran-3-yl)acetyl chloride is known for its high reactivity and instability, necessitating careful handling to prevent irritation and damage to the skin, eyes, and respiratory system. It is also important to store and handle this compound in a well-ventilated and controlled environment to ensure safety.
Uses
Used in Pharmaceutical Industry:
(2,5-dioxotetrahydrofuran-3-yl)acetyl chloride serves as a crucial reagent in organic synthesis, particularly for the preparation of various pharmaceuticals. Its unique structure and reactivity make it valuable in the development of new drugs and medicinal compounds.
Used in Agrochemical Industry:
In addition to its applications in pharmaceuticals, (2,5-dioxotetrahydrofuran-3-yl)acetyl chloride is also utilized in the synthesis of agrochemicals. Its role in this industry is to contribute to the development of effective and innovative products for agricultural use.
Used in Organic Synthesis Research:
(2,5-dioxotetrahydrofuran-3-yl)acetyl chloride plays a significant role in the field of organic synthesis and chemical research. Its properties allow researchers to explore new reactions and pathways, potentially leading to the discovery of novel compounds and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 77461-97-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,4,6 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77461-97:
(7*7)+(6*7)+(5*4)+(4*6)+(3*1)+(2*9)+(1*7)=163
163 % 10 = 3
So 77461-97-3 is a valid CAS Registry Number.
77461-97-3Relevant articles and documents
Facile synthesis of (R,R) and of (R,S) tricarballylic acid anhydride and imide derivatives
Hamad Elgazwy, Abdel-Sattar S.
, p. 665 - 673 (2000)
The diastereomeric mixture of (R)-2-(methoxycarbonylmethyl)-N-(R)-1-(1- phenylethyl) succinimide 11s and (S)-2-(methoxycarbonylmethyl)-N-(R)-1-(1- phenylethyl) succinimide 11a was synthesized by reaction of 2-(carboxymethyl) succinic anhydride 6 with (R)-(α)-methylbenzylamine in dry THF/room temperature/24 hrs. The diastereomeric mixture of 1-[(R)-(α)- Methylbenzylamideformyl)]propane-2,3-dicarboxylic acid anhydride 9s and 1-[(R)-(α)-methylbenzylamideformyl)]propane-2,3-dicarboxylic acid anhydride 9a was isolated as an intermediate under the reaction conditions. This diastereomeric mixture 9s/9a was also prepared by a different route via reaction of 1-(chloroformyl)propane-2,3-dicarboxylic acid anydride 12 with (R)-(α)-methylbenzylamine in the presence of DMA at 0°C for 24 hrs.
Synthesis of Functional Chelating Diphosphines Containing the Bisamino Moiety and the Use of These Materials in the Preparation of Water-Soluble Diphosphine Complexes of Transition Metals
Nuzzo, Ralph G.,Haynie, Sharon L.,Wilson, Michael E.,Whitesides, George M.
, p. 2861 - 2867 (2007/10/02)
Acylation of bisamine provides a flexible synthesis of functionalized chelating diphosphines.This reaction offers a route to diphosphine complexes of transition metals having a wide range of structures and physical properties and especially to water-soluble complexes.The aqueous solubility of the free ligands and of the complexes prepared from them depend on the ligand, on the metal, and on other materials (especially surfactants) present in the solution.We describe typical preparations of ligands and outline the properties of their complexes with certain transition metals.
