7748-58-5

Basic information

• Product Name: 5-BROMO-6-NITROBENZO(1,3)DIOXOLE
• Synonyms: 5-BROMO-6-NITRO-1,3-BENZODIOXOLE;5-BROMO-6-NITROBENZO(1,3)DIOXOLE;1,3-Benzodioxole, 5-broMo-6-nitro-;4-BroMo-5-nitro-1,2-Methylenedioxybenzene
• CAS NO: 7748-58-5
• Molecular Formula: C₇H₄BrNO₄
• Molecular Weight: 246.01
• Mol File: 7748-58-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 292 ºC at 760 mmHg
• Flash Point: 130.4 ºC
• Appearance: /
• Density: 1.912 g/cm³
• Vapor Pressure: 0.00328mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: 5-BROMO-6-NITROBENZO(1,3)DIOXOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-6-NITROBENZO(1,3)DIOXOLE(7748-58-5)
• EPA Substance Registry System: 5-BROMO-6-NITROBENZO(1,3)DIOXOLE(7748-58-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 7748-58-5(Hazardous Substances Data)

Usage

Description

5-BROMO-6-NITROBENZO(1,3)DIOXOLE is an organic compound characterized by the presence of a benzene ring with a bromine atom at the 5th position, a nitro group at the 6th position, and a dioxole (1,3) ring fused to it. 5-BROMO-6-NITROBENZO(1,3)DIOXOLE is known for its potential applications in the synthesis of various chemical and pharmaceutical products due to its unique structural features.

Uses

Used in Pharmaceutical Industry:
5-BROMO-6-NITROBENZO(1,3)DIOXOLE is used as an intermediate in the synthesis of bis-indolone-N-oxides, which possess significant biological and pharmacological importance. These bis-indolone-N-oxides are known for their diverse range of biological activities, including potential applications in the development of new drugs for the treatment of various diseases.
Used in Chemical Synthesis:
In the field of chemical synthesis, 5-BROMO-6-NITROBENZO(1,3)DIOXOLE serves as a valuable building block for the creation of more complex organic molecules. Its unique structural features, including the bromine and nitro groups, make it a versatile compound for use in various synthetic reactions, leading to the formation of a wide array of chemical products with different applications.

InChI:InChI=1/C7H4BrNO4/c8-4-1-6-7(13-3-12-6)2-5(4)9(10)11/h1-2H,3H2

Upstream product

• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 2635-13-4 1,2-(methylenedioxy)-4-bromobenzene 
• 120-57-0 piperonal 

Downstream Products

• 68560-11-2 2-methylthio-4,5-methylenedioxynitrobenzene 
• 93415-73-7 N-(2'-Methyl-6'-nitrophenyl)-5-amino-6-nitro-1,3-benzdioxol 
• 93415-80-6 N-(4'-Carboethoxy-2'-nitrophenyl)-5-amino-6-nitro-1,3-benzdioxol 
• 859979-85-4 4-bromo-2-methoxy-5-nitro-phenol 
• 75437-91-1 5-Bromo-4-nitro-2-phenoxymethoxy-phenol 
• 75437-92-2 4-Nitro-5-phenoxy-2-phenoxymethoxy-phenol 
• 93399-40-7 N-(2'-Nitrophenyl)-5-amino-6-nitro-1,3-benzdioxol 
• 108902-88-1 1-(2-bromophenylthio)-4,5-methylenedioxy-2-nitrobenzene 
• 158719-77-8 5-(2-bromophenylthio)-2-(2-bromophenylthiomethoxy)-4-nitrophenol 
• 158719-71-2 4-nitro-5-phenylthio-2-phenylthiomethoxyphenol 
• 67851-24-5 2-(6-Nitro-benzo[1,3]dioxol-5-ylsulfanyl)-phenylamine 
• 158719-79-0 5-(2-Amino-phenylsulfanyl)-2-(2-amino-phenylsulfanylmethoxy)-4-nitro-phenol 
• 1027545-05-6 4-Amino-5-phenylsulfanyl-2-phenylsulfanylmethoxy-phenol 
• 1027182-42-8 2-Chloro-N-[2-(6-nitro-benzo[1,3]dioxol-5-ylsulfanyl)-phenyl]-acetamide 

Relevant articles and documents

HETEROCYCLIC LSF INHIBITORS AND THEIR USES

The present invention is directed to heterocyclic SV40 Factor (LSF) inhibitors and their uses. In some implementations, the present invention discloses small-molecule compounds of Formula (I). In some implementations, the compounds of Formula (I) are used

Synthesis of the 3,4,5-trimethoxy-2-(3,4-methylenedioxy-6-nitrophenyl) benzaldehyde for divergent preparation of cytotoxic biaryls

The regioselective synthesis of the 3,4,5-trimethoxy-2-(3,4-methylenedioxy- 6-nitrophenyl)benzaldehyde as key intermediate for divergent preparation of cytotoxic biaryl lignans was achieved in three steps from commercially available starting materials. Re

Derivatives of 1,3-benzdioxoles, 52. Preparation and reactions of 1,3-dioxolo[4,5-b]phenazines

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