77509-36-5

Basic information

• Product Name: 2-phenyl-naphthalene-1,4-diol
• CAS NO: 77509-36-5
• Molecular Weight: 236.27
• Mol File: 77509-36-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenyl-naphthalene-1,4-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-naphthalene-1,4-diol(77509-36-5)
• EPA Substance Registry System: 2-phenyl-naphthalene-1,4-diol(77509-36-5)

Safety Data

• Hazardous Substances Data: 77509-36-5(Hazardous Substances Data)

Upstream product

• 7664-93-9 sulfuric acid 
• 2348-77-8 2-phenyl[1,4]naphthoquinone 
• 130-15-4 [1,4]naphthoquinone 
• 98-80-6 phenylboronic acid 

Downstream Products

• 59832-94-9 1,4-diacetoxy-2-phenyl-naphthalene 

Relevant articles and documents

Synthesis of Functionalized Dihydrocoumarins by NHC-Catalyzed [3 + 3] Annulation of Enals with 2-Substituted Naphthoquinones

The [3 + 3] annulation of α,β-unsaturated aldehydes with 2-substituted 1,4-naphthoquinones allowing the facile synthesis of functionalized dihydrocoumarins catalyzed by N-heterocyclic carbene (NHC) is reported. The initially formed NHC-homoenolates underwent an efficient Michael-isomerization-lactonization cascade to furnish the products. Preliminary studies on mechanism shed light on the homoenolate pathway over the intermediacy of the α,β-unsaturated acylazolium intermediates. Moreover, using chiral NHCs, the desired products were formed in up to 49% yield and 99:1 er.