77523-96-7

Basic information

• Product Name: 1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea
• CAS NO: 77523-96-7
• Molecular Formula: C₁₆H₁₆N₄S
• Molecular Weight: 296.39
• Mol File: 77523-96-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 525°C at 760 mmHg
• Flash Point: 271.3°C
• Density: 1.336g/cm³
• Vapor Pressure: 4.07E-11mmHg at 25°C
• Refractive Index: 1.757
• CAS DataBase Reference: 1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea(77523-96-7)
• EPA Substance Registry System: 1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea(77523-96-7)

Safety Data

• Hazardous Substances Data: 77523-96-7(Hazardous Substances Data)

Usage

Description

1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea is a chemical compound with the molecular formula C18H18N4S. It is a thiourea derivative that contains a benzimidazole moiety and a 3-methylphenyl group. 1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea is known for its diverse biological activities, which include anti-inflammatory, antiviral, and antitumor properties. Its unique structure and potential biological activities make it a promising candidate for pharmaceutical applications. The benzimidazole core also makes it a candidate for drug development, as benzimidazoles are widely used in medicinal chemistry for the synthesis of various bioactive compounds. Further research and studies are needed to fully understand the pharmacological potential and applications of this compound.

Uses

Used in Pharmaceutical Industry:
1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea is used as a potential pharmaceutical agent for its diverse biological activities, including anti-inflammatory, antiviral, and antitumor properties. Its unique structure and the presence of a benzimidazole core make it a promising candidate for the development of new drugs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea is used as a building block for the synthesis of various bioactive compounds. The benzimidazole core is a common structural element in many drugs, and this compound's potential for further modification and development makes it a valuable asset in the creation of new pharmaceuticals.
Used in Drug Development:
1-(1H-benzimidazol-2-ylmethyl)-3-(3-methylphenyl)thiourea is used as a starting point for drug development due to its potential biological activities and unique structure. Further research and studies are necessary to explore its full pharmacological potential and to determine its suitability for specific therapeutic applications.

Upstream product

• 5805-57-2 2-Aminomethylbenzimidazole 
• 621-30-7 3-methylphenyl isothiocyanate 
• 5993-91-9 2-(aminomethyl)benzimidazole dihydrochloride 

Downstream Products

• 77524-03-9 (3H-Benzo[d]imidazo[1,5-a]imidazol-1-yl)-m-tolyl-amine 
• 89334-77-0 3-(1H-Benzoimidazol-2-ylmethyl)-2-[(Z)-m-tolylimino]-thiazolidin-4-one 

Relevant articles and documents

Syntheses and in vitro antimicrobial evaluation of some benzimidazol-2-ylmethylthioureas, benzimidazol-2-ylacetylthiosemicarbazides and products of their condensation with monochloroacetic acid

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The cyclodesulfurization of thio-compounds. XX. Synthesis of some 1-substituted amino-3H-imidazo [1,5-a] benzimidazole derivatives by cyclodesulfurization of various benzimidazole-thioureas with dicyclohexylcarbodiimide (DCCD)

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