77546-39-5 Usage
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 77546-39-5 differently. You can refer to the following data:
1. Labelled Testosterone (T155000). Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.
Controlled substance (anabolic steroid). Androgen.
2. Labelled Testosterone, which is secreted by the testis and is converted to dihydrotestosterone in the target tissue where is appears to mediate many of the biological actions of testosterone.
CONTROLLED SUBSTANC
Check Digit Verification of cas no
The CAS Registry Mumber 77546-39-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,5,4 and 6 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77546-39:
(7*7)+(6*7)+(5*5)+(4*4)+(3*6)+(2*3)+(1*9)=165
165 % 10 = 5
So 77546-39-5 is a valid CAS Registry Number.
77546-39-5Relevant articles and documents
The Selective Protection of the 3-Ketone Functions of Steroids as Heptafluoro-p-tolyl Enol Ethers
Jarman, Michael,McCague, Raymond
, p. 1129 - 1134 (2007/10/02)
Conjugated and unconjugated 3-ketone functions in steroids react with octafluorotoluene at above 100 deg C in the presence of caesium fluoride to give heptafluoro-p-tolyl enol ethers.The related but unusually reactive Wieland-Miescher ketone (11) reacted at room temperature in the presence of tetra-n-butylammonium fluoride.Enones were regenerated from their derivatives by acidic hydrolysis.Hydrolysis of the derivative (10) of 4,5α-dihydroxytestosterone was slu but sodium methoxide regenerated the parent steroid.The methods have been applied in a synthesis of deuterium-labelled testosterone.
