77588-52-4

Basic information

• Product Name: 1-Phenyl-1,4-octanedione
• Synonyms: 1-Phenyl-1,4-octanedione
• CAS NO: 77588-52-4
• Molecular Weight: 218.296
• Mol File: 77588-52-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Phenyl-1,4-octanedione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-1,4-octanedione(77588-52-4)
• EPA Substance Registry System: 1-Phenyl-1,4-octanedione(77588-52-4)

Safety Data

• Hazardous Substances Data: 77588-52-4(Hazardous Substances Data)

Upstream product

• 110-62-3 pentanal 
• 583-06-2 3-benzoylacrylic acid 
• 98-88-4 benzoyl chloride 
• 364045-18-1 4-cyano-4-morpholino-4-phenyl-N-methoxy-N-methylbutyramide 
• 15190-10-0 morpholin-4-yl-phenyl-acetonitrile 

Relevant articles and documents

Palladium-Catalyzed Reductive Coupling of Acid Chlorides with β-Stannyl Enones: Synthesis of 1,4-Diketones and Mechanistic Aspects

The palladium-catalyzed coupling of acid chlorides with (E)-1,2-bis(tri-n-butylstannyl)ethene or β-stannyl enones gives butane-1,4-diones directly by reduction of the intermediate enedicarbonyl intermediate.The double bond conjugated with a single carbonyl group was not significantly reduced.The generality of the method is illustrated by two syntheses of the 1,4-diketone ipomeanine.By performing the reaction at lower temperatures, α,β-unsaturated 1,4-diketones can also be prepared.The reduction of the intermediate α,β-unsaturated 1,4-diketones probably proceeds by insertion of a palladium hydride, formed in situ by reaction of a Pd(II) complex with Bu3SnCl, followed by hydrolysis of the intermediate palladium enolate.

From allylic alcohols to saturated carbonyls using Fe(CO)5 as catalyst: Scope and limitation studies and preparation of two perfume components

The direct conversion of allylic alcohols to saturated carbonyls, using Fe(CO)5 as a catalyst, offers good synthetic potential. Mono-, di- and even trisubstituted alkenes bearing various alkyl, aryl and electronwithdrawing groups on the allylic system give good to excellent yields of rearranged products. Limitations occur mainly with polyunsaturated derivatives. This reaction was applied to a short and efficient synthesis of cyclamen aldehyde and foliaver.