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77632-95-2

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77632-95-2 Usage

General Description

Heroin-7,8-oxide, also known as 6-MAM-7,8-oxide, is a derivative and potentially active metabolite of heroin. This chemical compound is an opiate substance believed to contribute to the analgesic (pain relieving) effects of heroin. It has not been extensively studied and hence, its full pharmacology is not completely understood currently. However, it could largely contribute to understanding the biology of heroin use and addiction. Its potential role in the toxicity or the long-term health effects of heroin use is also not well-defined yet.

Check Digit Verification of cas no

The CAS Registry Mumber 77632-95-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,6,3 and 2 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 77632-95:
(7*7)+(6*7)+(5*6)+(4*3)+(3*2)+(2*9)+(1*5)=162
162 % 10 = 2
So 77632-95-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H23NO6/c1-9(23)25-13-5-4-11-8-12-15-17-18(27-17)19(26-10(2)24)20-21(15,6-7-22(12)3)14(11)16(13)28-20/h4-5,12,15,17-20H,6-8H2,1-3H3/t12-,15-,17+,18+,19+,20-,21-/m1/s1

77632-95-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Diacetylmorphine 7,8-oxide

1.2 Other means of identification

Product number -
Other names Heroin 7,8-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:77632-95-2 SDS

77632-95-2Synthetic route

acetic anhydride
108-24-7

acetic anhydride

morphine-7,8-oxide
77632-94-1

morphine-7,8-oxide

heroin-7,8-oxide
77632-95-2

heroin-7,8-oxide

Conditions
ConditionsYield
In pyridine62.9%
3-methoxymethylmorphinone
77632-93-0

3-methoxymethylmorphinone

heroin-7,8-oxide
77632-95-2

heroin-7,8-oxide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 81 percent / H2O2, NaOH / methanol; H2O
2: 66 percent / NaBH4 / methanol
3: 73.1 percent / 1N HCl / 20 °C
4: 62.9 percent / pyridine
View Scheme
3-methoxymethylmorphinone-7,8-oxide
77648-71-6

3-methoxymethylmorphinone-7,8-oxide

heroin-7,8-oxide
77632-95-2

heroin-7,8-oxide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 66 percent / NaBH4 / methanol
2: 73.1 percent / 1N HCl / 20 °C
3: 62.9 percent / pyridine
View Scheme
3-methoxymethylmorphine-7,8-oxide
77632-96-3

3-methoxymethylmorphine-7,8-oxide

heroin-7,8-oxide
77632-95-2

heroin-7,8-oxide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 73.1 percent / 1N HCl / 20 °C
2: 62.9 percent / pyridine
View Scheme

77632-95-2Downstream Products

77632-95-2Relevant articles and documents

Synthesis and analgesic activity of morphine-7,8-oxide and heroin-7,8-oxide

Miyata,Uba,Watanabe,Hirobe

, p. 3722 - 3724 (2007/10/02)

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