7764-45-6Relevant articles and documents
STEROID DERIVATIVE REGULATORS, METHOD FOR PREPARING THE SAME, AND USES THEREOF
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Paragraph 0245-0246, (2020/12/22)
The present invention relates to steroid derivative regulators, a method for preparing the same, and uses thereof. Specifically, the present invention relates to a compound as shown in formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and uses thereof as a regulator of GABA A receptor for treating depression, convulsion, Parkinson's disease, and nervous system diseases, wherein the substituents of the formula (I) are as defined in the description.
Synthesis of 19,19-Difluoro Steroids and of Novel B-Ring-expanded Steroids
Drew, Michael G. B.,Mann, John,Pietrzak, Barbara
, p. 1191 - 1192 (2007/10/02)
A site-selective fluorination of 10-formylnortestosterone 17-benzoate (4) which allows access to 19,19-difluoro steroids is described, and an associated rearrangement reaction yields the novel abeo-testosterone derivative (6) and thence the homoestradiol