77651-37-7

Basic information

• Product Name: 2-amino-4,5-dimethylfuran-3-carboxamide
• CAS NO: 77651-37-7
• Molecular Formula: C₇H₁₀N₂O₂
• Molecular Weight: 154.1665
• Mol File: 77651-37-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 215.8°C at 760 mmHg
• Flash Point: 84.3°C
• Density: 1.225g/cm³
• Vapor Pressure: 0.145mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: 2-amino-4,5-dimethylfuran-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4,5-dimethylfuran-3-carboxamide(77651-37-7)
• EPA Substance Registry System: 2-amino-4,5-dimethylfuran-3-carboxamide(77651-37-7)

Safety Data

• Hazardous Substances Data: 77651-37-7(Hazardous Substances Data)

Usage

Chemical compound type

Furan derivative

Functional groups

Amino group, two methyl groups, carboxamide group

Potential applications

Pharmaceutical industry, building block for synthesis of bioactive molecules

Structure

Contains amino group, two methyl groups, carboxamide functional group

Biological activity

Potential due to structure, further research needed to determine exact properties and uses

Upstream product

• 5117-88-4 2-amino-3-cyano-4,5-dimethylfuran 

Relevant articles and documents

SUBSTITUTED 2- AMIDOQUINAZOL-4-ONES AS MATRIX METALLOPROTEINASE-13 INHIBITORS

The present invention provides a novel amide derivative having a matrix metalloproteinase inhibitory activity, and useful as a pharmaceutical agent, which is a compound represented by the formula (I) wherein ring A is an optionally substituted, nitrogen containing heterocycle, ring B is an optionally substituted monocyclic homocycle or an optionally substituted monocyclic heterocycle, Z is N or NR1 (R1 is a hydrogen atom or an optionally substituted hydrocarbon group), is a single bond or a double bond, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, X is an optionally substituted spacer having 1 to 6 atoms, ring C is (1) an optionally substituted homocycle or (2) an optionally substituted heterocycle other than a ring represented by (II) (X′ is S, O, SO, or CH2), and at least one of ring B and ring C has substituent(s), provided that N-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]2 hydroxypropyl}5,6 dimethyl 4 oxo 1,4 dihydrothieno[2,3-d]pyrimidine-2-carboxamide is excluded, or a salt thereof.