77674-99-8

Basic information

• Product Name: AI 77B
• Synonyms: AI 77B;(3S,4S,5S)-3-Amino-4,5-dihydroxy-6-oxo-6-[[(1S)-1-[(3S)-1-oxo-8-hydroxy-3,4-dihydro-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]hexanoic acid;(3S,4S,5S)-3-Amino-4,5-dihydroxy-6-oxo-6-[[(S)-1-[(S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]hexanoic acid
• CAS NO: 77674-99-8
• Molecular Formula: C₂₀H₂₈N₂O₈
• Molecular Weight: 0
• Mol File: 77674-99-8.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 830.3°C at 760 mmHg
• Flash Point: 456°C
• Appearance: /
• Density: 1.381g/cm³
• Vapor Pressure: 3.2E-29mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: AI 77B(CAS DataBase Reference)
• NIST Chemistry Reference: AI 77B(77674-99-8)
• EPA Substance Registry System: AI 77B(77674-99-8)

Safety Data

• Hazardous Substances Data: 77674-99-8(Hazardous Substances Data)

Usage

General Description

AI 77B is a chemical compound that is commonly used as an insecticide and acaricide. It is primarily used to control pests in agricultural settings, particularly on crops such as cotton, citrus fruits, and vegetables. The active ingredient in AI 77B is known as fenazaquin, which works by disrupting the nervous system of insects and mites, leading to paralysis and eventual death. It is classified as a non-systemic insecticide, meaning it remains on the surface of plants and is not taken up into the plant tissue. AI 77B is considered to have low to moderate toxicity to humans and is generally safe when used as directed. However, it is important to follow safety precautions and usage guidelines when handling and applying this chemical.

InChI:InChI=1/C20H28N2O8/c1-9(2)6-12(22-19(28)18(27)17(26)11(21)8-15(24)25)14-7-10-4-3-5-13(23)16(10)20(29)30-14/h3-5,9,11-12,14,17-18,23,26-27H,6-8,21H2,1-2H3,(H,22,28)(H,24,25)/t11-,12-,14-,17-,18-/m0/s1

Upstream product

• 77682-31-6 (S)-2-[(2S,3S)-3-amino-5-oxotetrahydrofuran-2-yl]-2-hydroxy-N-{(S)-1-[(S)-8-hydroxy-1-oxoisochroman-3-yl]-3-methylbutyl}acetamide 
• 86594-32-3 amicoumacin C hydrochloride 
• 77675-03-7 AI-77-G 
• 118868-06-7 ((S)-2-Cyano-1-{(4S,5S)-5-[(S)-1-((S)-8-hydroxy-1-oxo-isochroman-3-yl)-3-methyl-butylcarbamoyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-ethyl)-carbamic acid tert-butyl ester 
• 147804-75-9 (3S)-3-<(1'S)-1'-<<(3''-amino-5''-O-(3-chlorobenzoyl)-2'',3''-dideoxy-α-D-ribo-hexaro-1'',4''-lactone)-6''-oyl>amino>-3'-methylbutyl>-3,4-dihydro-8-hydroxy-1H-2-benzopyran-1-one 
• 118868-07-8 (S)-2-((2S,3S)-3-Amino-5-imino-tetrahydro-furan-2-yl)-2-hydroxy-N-[(S)-1-((S)-8-hydroxy-1-oxo-isochroman-3-yl)-3-methyl-butyl]-acetamide; hydrochloride 
• 365449-64-5 (4S,5S)-4-Benzyloxycarbonylmethyl-5-{(S)-benzyloxy-[(S)-1-((S)-8-hydroxy-1-oxo-isochroman-3-yl)-3-methyl-butylcarbamoyl]-methyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 540770-27-2 (4S,5S)-4-Allyl-5-((S)-1-benzyloxy-2-oxo-ethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 365449-52-1 (4S,5S)-4-Allyl-5-((S)-benzyloxy-carboxy-methyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 540770-28-3 (4S,5S)-5-{(S)-Benzyloxy-[(S)-1-((S)-8-methoxy-1-oxo-isochroman-3-yl)-3-methyl-butylcarbamoyl]-methyl}-2,2-dimethyl-4-(2-oxo-ethyl)-oxazolidine-3-carboxylic acid tert-butyl ester 
• 365449-62-3 (4S,5S)-4-Allyl-5-{(S)-benzyloxy-[(S)-1-((S)-8-methoxy-1-oxo-isochroman-3-yl)-3-methyl-butylcarbamoyl]-methyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 540770-29-4 (4S,5S)-5-{(S)-Benzyloxy-[(S)-1-((S)-8-methoxy-1-oxo-isochroman-3-yl)-3-methyl-butylcarbamoyl]-methyl}-4-carboxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 365449-63-4 (4S,5S)-4-Benzyloxycarbonylmethyl-5-{(S)-benzyloxy-[(S)-1-((S)-8-methoxy-1-oxo-isochroman-3-yl)-3-methyl-butylcarbamoyl]-methyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 

Downstream Products

• 77675-03-7 AI-77-G 
• 77675-03-7 6-<<1-(2-carboxy-3-hydroxyphenyl)-2-hydroxy-5-methylhex-3-yl>amino>-4,5-dihydroxy-6-oxo-3-ammoniohexanoate 
• 78683-77-9 <6-<<1-(3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl>amino>-4,5-dihydroxy-6-oxo-3-hexanamido>ammonium chloride 
• 61-90-5 L-leucine 

Relevant articles and documents

Bacilosarcins A and B, novel bioactive isocoumarins with unusual heterocyclic cores from the marine-derived bacterium Bacillus subtilis

Two novel isocoumarins, bacilosarcins A (1) and B (2) were isolated from a culture broth of the marine-derived bacterium Bacillus subtilis TP-B0611. The structures and absolute configurations of 1 and 2 were determined on the basis of spectroscopic analyses and chemical conversions. Compound 1 possesses an unprecedented 3-oxa-6,9-diazabicyclo[3.3.1]nonane ring system while 2 has a 2-hydroxymorpholine moiety that is rare in nature. These compounds showed growth inhibition against barnyard millet.

Total Synthesis of Originally Proposed and Revised Structure of Hetiamacin A

The first total synthesis of the originally proposed and correct structures of hetiamacin A has been accomplished via Wittig olefination and Sharpless asymmetric dihydroxylation reaction. These total syntheses culminated in the stereostructural confirmati

Stereoselective synthesis of pseudopeptide microbial agent AI-77-B.

[structure: see text]. An efficient and highly stereoselective synthesis of the gastroprotective natural product AI-77-B is described. The stereocenters of the hydroxy amino acid moiety were generated by an ester-derived titanium-enolate-mediated syn-aldo