77679-27-7

Basic information

• Product Name: Guanidine, 3-(iodo-131I)phenylmethyl-
• Synonyms: Guanidine, 3-(iodo-131I)phenylmethyl-;1-[[3-(131I)Iodophenyl]methyl]guanidine;1-[m-(131I)Iodobenzyl]guanidine;131I-MIBG;Iobenguane(131I);m-(131I)Iodobenzylguanidine;Metaiodobenzylguanidine(131I);1-(3-iodobenzyl)guanidine
• CAS NO: 77679-27-7
• Molecular Formula: C8H10 I N3
• Molecular Weight: 0
• Mol File: 77679-27-7.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Density: 1.85g/cm³
• Refractive Index: 1.683
• CAS DataBase Reference: Guanidine, 3-(iodo-131I)phenylmethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Guanidine, 3-(iodo-131I)phenylmethyl-(77679-27-7)
• EPA Substance Registry System: Guanidine, 3-(iodo-131I)phenylmethyl-(77679-27-7)

Safety Data

• Hazardous Substances Data: 77679-27-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H10IN3/c9-7-3-1-2-6(4-7)5-12-8(10)11/h1-4H,5H2,(H4,10,11,12)/i9+4

Upstream product

• 87862-25-7 meta-Iodobenzylguanidinium sulfate 
• 420-04-2 CYANAMID 
• 222729-15-9 1-(-3-bromobenzyl)-2,2,5,5-tetramethyl-1,2,5-azadisilolidine 
• 80663-95-2 (3-iodobenzyl)guanidine 
• 80663-96-3 m-Iodobenzylguanidine hemisulfate 

Relevant articles and documents

Polymer-supported radiopharmaceuticals: [131I]MIBG and [123I]MIBG

A new method has been developed that produces no-carrier-added [131I]MIBG in ≥ 90% radiochemical yield and high chemical purity. Isolation and purification are simple involving just filtration and absorption and desorption onto a C18 Sep-Pak(TM) cartridge. No-carrier-added material should avoid the potential pharmacological side effects accompanying the current method of production.

A tin precursor for the synthesis of no-carrier-added [*I]MIBG and [211At]MABG

Radioiodinated MIBG has shown considerable promise as an imaging agent for cardiac and oncologic applications, and also as a targeted radio therapeutic for treating patients with neuroendocrine tumors. This radiolabeled agent, synthesized at a no-carrier-

A suitable for the clinical application of carrier-free [* I] MIBG preparation method and application of (by machine translation)

The invention provides a method suitable for the clinical application of carrier-free [* I] MIBG preparation method, through three ding xi base animal pen guanidine is dissolved in alcohol solvent and added to the amount of phosphate buffer in

A Highly Efficient Copper-Mediated Radioiodination Approach Using Aryl Boronic Acids

A convenient and quantitative radioiodination method by copper-mediated cross-coupling of aryl boronic acids was developed. The mild labeling conditions, ready availability of the boronic acid substrate, simple operation, broad functional group tolerance and excellent radiochemical yield (RCY) make this a practical strategy for radioiodine labeling without further purification.