77708-66-8Relevant articles and documents
Total Synthesis of Benzofuran-Based Aspergillusene B via Halogenative Aromatization of Enones
Bhatti, Aisha,Grabovyi, Gennadii A.,Mohr, Justin T.
, (2020/06/08)
A novel "non-aromatic pool" synthetic strategy for the synthesis of benzofuran-based natural products via oxidative haloaromatization of enones is reported. This approach is successfully applied in the first total synthesis of the natural product aspergil
Formation of meta-arylsulfanyl- and meta-(alkylsulfanyl)phenols from cyclohexane-1,3-diones
Do Van Thanh, Nhan,Patra, Subrata,Clive, Derrick L.J.
, p. 4343 - 4350 (2018/07/13)
Reaction of cyclohexane-1,3-diones with TsCl/Et3N and treatment of the resulting 3-(tosyloxy)cyclohex-2-en-1-ones with aryl- or alkyl thiols and K2CO3 in MeCN gives 3-(arylsulfanyl)cyclohex-2-en-1-ones or 3-(alkylsulfanyl)cyclohex-2-en-1-ones, respectively. These compounds are easily brominated at C-2 by using NBS in MeCN; exposure to DBU in MeCN at room temperature then causes aromatization to afford meta-arylsulfanyl- and meta-(alkylsulfanyl)phenols.
Asymmetric Sequential Cu-Catalyzed 1,6/1,4-Conjugate Additions of Hard Nucleophiles to Cyclic Dienones: Determination of Absolute Configurations and Origins of Enantioselectivity
Blons, Charlie,Morin, Marie S. T.,Schmid, Thibault E.,Vives, Thomas,Colombel-Rouen, Sophie,Baslé, Olivier,Reynaldo, Thibault,Covington, Cody L.,Halbert, Stéphanie,Cuskelly, Sean N.,Bernhardt, Paul V.,Williams, Craig M.,Crassous, Jeanne,Polavarapu, Prasad L.,Crévisy, Christophe,Gérard, Hélène,Mauduit, Marc
supporting information, p. 7515 - 7525 (2017/06/06)
The first stereocontrolled Cu-catalyzed sequential 1,6/1,4-asymmetric conjugate addition (ACA) of C-metalated hard nucleophiles to cyclic dienones is reported. The use of DiPPAM (diphenylphosphinoazomethinylate) followed by a phosphoramidite as the stereo
