77744-52-6Relevant articles and documents
Isolation and biomimetic total synthesis of tomentodiones A-B, terpenoid-conjugated phloroglucinols from the leaves of: Rhodomyrtus tomentosa
Liu, Hong-Xin,Chen, Kai,Tang, Gui-Hua,Yuan, Yun-Fei,Tan, Hai-Bo,Qiu, Sheng-Xiang
, p. 48231 - 48236 (2016)
Tomentodiones A (1) and B (2), a pair of C-11′ epimers of caryophyllene-conjugated phloroglucinols with an unprecedented skeleton, were isolated from the leaves of Rhodomyrtus tomentosa. Their structures were elucidated through the application of extensiv
Mn(III)-catalyzed aerobic oxidation of 2-alkenyl-1,3-diketone enols. Synthesis of 1,2-dioxin-3-ols and natural phytohormone G factors
Oka, Sousuke,Hashimoto, Shintaro,Hisano, Kazuki,Nishino, Hiroshi
supporting information, (2022/01/23)
The Mn(III)-catalyzed aerobic oxidation of 2-alkenyl-1,3-diketone enols is described. The reaction produced unsaturated endoperoxides, i.e., 1,2-dioxin-3-ols, via resonance stabilized alkenyldiketone radicals. This convenient and eco-friendly reaction was
Application of myrtle ketone compound in preparation of novel coronavirus SARS-CoV-2 medicine
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Paragraph 0045; 0048; 0053-0054, (2021/12/07)
The invention discloses application of myrtle ketone compounds in preparation of novel coronavirus SARS-CoV-2 medicaments. The myrtle ketone compound has obvious inhibition effect on novel coronavirus SARS-CoV-2. Mechanisms include, but are not limited to, inhibition of new coronavirus SARS-CoV-2 into cells, preventing the replication of new coronavirus SARS-CoV-2 in the host cell, and timely modulating apoptosis of infected cells. To the myrtle ketone compound provided by the invention, the novel coronavirus SARS-CoV-2 has a remarkable inhibiting effect, and the cytotoxicity is relatively small. It can therefore be used for the prophylaxis or treatment of neoplastic pneumonitis. The invention is expected to provide new candidate drug molecules for clinic treatment of nebrodensis.
The Biomimetic Total Syntheses of the Antiplasmodial Tomentosones A and B
Dong, Chunmao,Hu, Yingjie,Huo, Luqiong,Liu, Hongxin,Tan, Haibo,Wu, Guiyun,Yuan, Yunfei,Zhang, Xiao
supporting information, p. 8007 - 8011 (2020/11/02)
The first biomimetic total syntheses of natural phloroglucinols tomentosones A and B and their analogues have been accomplished. The synthetic strategy primarily referred to the potential biosynthetic precursors and their possible sequence of segments ass