77779-90-9Relevant articles and documents
Synthesis and pharmacological evaluation of pyrazolo[4,3-c]quinolinones as high affinity GABAA-R ligands and potential anxiolytics
López Rivilli, Marisa J.,Turina, Anahí V.,Bignante, Elena A.,Molina, Victor H.,Perillo, María A.,Bri?on, Margarita C.,Moyano, Elizabeth L.
, p. 3967 - 3974 (2018/06/29)
The synthesis, in vitro ligand binding study and in vivo Elevated Plus Maze test (EPM) of a series of pyrazolo[4,3-c]quinolin-3-ones (PQs) are reported. Multistep synthesis of PQs started from anilines and diethyl 2-(ethoxymethylene)malonate to give the q
Synthesis and antiviral activities of new pyrazolo[4,3-c]quinolin-3-ones and their ribonucleoside derivatives
De Oliveira, Mara R. P.,Alves, Thatyana R.,Pinto, Angelo C.,Pereira, Helena De S.,Leao-Ferreira, Luiz R.,Moussatche, Nissin,Frugulhetti, Izabel Christina De P. P.,Ferreira, Vitor F.,De Souza, Maria Cecilia B. V.
, p. 735 - 748 (2007/10/03)
Several new pyrazolo[4,3-c]quinolin-3-one ribonucleosides (5a-g) and their corresponding heterocycle moieties (3a-g) were synthesized and evaluated against vaccinia virus (VV) and herpes simplex virus type 1 (HSV-1). The derivatives 3c and 3d showed modes
