77784-23-7Relevant articles and documents
Synthesis and structure-activity relationships of a series of aporphine derivatives with antiarrhythmic activities and acute toxicity
Wang, Hui,Cheng, Xin,Kong, Shujun,Yang, Zixian,Wang, Hongmei,Huang, Qiuyan,Li, Jingyu,Chen, Cheng,Ma, Yunshu
, (2016/12/16)
Some aporphine alkaloids, such as crebanine, were found to present arrhythmic activity and also higher toxicity. A series of derivatives were synthesized by using three kinds of aporphine alkaloids (crebanine, isocorydine, and stephanine) as lead compound