77806-87-2

Basic information

• Product Name: 2--5,5-dimethyl-1,3,2-dioxaphosphinan-2-one
• Synonyms: 2--5,5-dimethyl-1,3,2-dioxaphosphinan-2-one
• CAS NO: 77806-87-2
• Molecular Weight: 256.238
• Mol File: 77806-87-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2--5,5-dimethyl-1,3,2-dioxaphosphinan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2--5,5-dimethyl-1,3,2-dioxaphosphinan-2-one(77806-87-2)
• EPA Substance Registry System: 2--5,5-dimethyl-1,3,2-dioxaphosphinan-2-one(77806-87-2)

Safety Data

• Hazardous Substances Data: 77806-87-2(Hazardous Substances Data)

Upstream product

• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 4090-60-2 5,5-dimethyl-1,3-dioxaphosphorinan-2-oxide 
• 100-52-7 benzaldehyde 

Downstream Products

• 1392226-20-8 2-[((4-chloro-2-methylphenoxy)acetyl)oxy](phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1392226-14-0 2-[((2-chlorophenoxy)acetyl)oxy](phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1392226-18-4 2-[((4-chloro-3-methylphenoxy)acetyl)oxy](phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1392226-16-2 2-[((4-chlorophenoxy)acetyl)oxy](phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1392226-00-4 2-[((2,4-dichlorophenoxy)acetyl)oxy](phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 186968-63-8 2-(Bromo-phenyl-methyl)-5,5-dimethyl-[1,3,2]dioxaphosphinane 2-oxide 
• 186968-62-7 2-(Chloro-phenyl-methyl)-5,5-dimethyl-[1,3,2]dioxaphosphinane 2-oxide 
• 106986-16-7 1,4-diphenyl-2-methyl-1-butanone 
• 1395103-38-4 2-phenoxyacetoxy(phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1395103-32-8 2-(2-chloro-4-fluorophenoxyacetoxy)(phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1395103-31-7 2-(2-fluoro-4-chlorophenoxyacetoxy)(phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1395103-30-6 2-(4-fluorophenoxyacetoxy)(phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1395103-29-3 2-(3-trifluoromethylphenoxyacetoxy)(phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 
• 1395103-28-2 2-(2-fluorophenoxyacetoxy)(phenyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one 

Relevant articles and documents

Cobalt-Catalyzed Markovnikov-Selective Radical Hydroacylation of Unactivated Alkenes with Acylphosphonates

Acylphosphonates having the 5,5-dimethyl-1,3,2-dioxophosphinanyl skeleton are developed as efficient intermolecular radical acylation reagents, which enable the cobalt-catalyzed Markovnikov hydroacylation of unactivated alkenes at room temperature under mild conditions. The protocol exhibits broad substrate scope and wide functional group compatibility, providing branched ketones in satisfactory yields. A mechanism involving the Co-H mediated hydrogen atom transfer and subsequent trapping of alkyl radicals by acylphosphonates is proposed.

Design, synthesis and herbicidal activity of novel cyclic phosphonates with diaryl ethers containing pyrimidine

Thirteen novel cyclic phosphates were rationally designed and synthesized by introducing diary ethers containing pyrimidine. All the target compounds were characterized by 1H, 13C, 31P NMR and HRMS. The test of herbicidal activity indicated that most of the compounds showed good herbicidal activities against Amaranthus retroflexus. The compounds IA-2 (1-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)propyl-2-((4,6-dimethoxypyrimidin-2-yl)oxy)benzoate) and IA-3 ((5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)(phenyl)methyl-2-((4,6-dimethoxypyrimidin-2-yl)oxy)benzoate) exhibited remarkable post-emergency herbicidal activity against the tested monocotyledonous weed at the dosage of 112.5 g ai/ha.

Synthesis and Herbicidal Activity of α-(Substituted Phenoxybutyryloxy or Valeryloxy)alkylphosphonates and 2-(Substituted Phenoxybutyryloxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one

On the basis of our work on the modification of alkylphosphonates 1, a series of α-(substituted phenoxybutyryloxy or valeryloxy)alkylphosphonates (4-5) and 2-(substituted phenoxybutyryloxy)alkyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one (6) were designed and synthesized. The bioassay results indicated that 14 of title compounds 4 exhibited significant postemergence herbicidal activity against velvetleaf, common amaranth, and false daisy at 150 g ai/ha. Compounds 5 were inactive against all tested weeds. Compounds 6 exhibited moderate to good inhibitory effect against the tested dicotyledonous weeds. Structure-activity relationship (SAR) analyses showed that the length of the carbon chain as linking bridge had a great effect on the herbicidal activity. Broad-spectrum tests of compounds 4-1, 4-2, 4-9, 4-30, and 4-36 were carried out at 75 g ai/ha. Especially, 4-1 exhibited 100% inhibition activity against the tested dicotyledonous weeds, which was higher than that of glyphosate.