77853-40-8

Basic information

• Product Name: 1,3-Benzodioxole, 5-[[(4-methylphenyl)sulfonyl]methyl]-
• CAS NO: 77853-40-8
• Molecular Formula: C15H14O4S
• Molecular Weight: 290.34
• Mol File: 77853-40-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-Benzodioxole, 5-[[(4-methylphenyl)sulfonyl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzodioxole, 5-[[(4-methylphenyl)sulfonyl]methyl]-(77853-40-8)
• EPA Substance Registry System: 1,3-Benzodioxole, 5-[[(4-methylphenyl)sulfonyl]methyl]-(77853-40-8)

Safety Data

• Hazardous Substances Data: 77853-40-8(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 112101-21-0 N,N,N-trimethyl-(3',4'-methylenedioxyphenyl)methylammonium iodide 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 20850-43-5 5-(chloromethyl)-1,3-benzodioxole 

Downstream Products

• 1563173-93-2 C₂₃H₁₈O₆S 
• 77853-43-1 4-Benzo[1,3]dioxol-5-yl-4-(toluene-4-sulfonyl)-butyronitrile 

Relevant articles and documents

A general and practical sulfonylation of benzylic ammonium salts with sulfonyl hydrazides for the synthesis of sulfones

A practical and efficient approach adopting transition-metal-free cross-coupling of sulfonyl hydrazides with benzyl ammonium salts has been developed to synthesize benzyl sulfones using Cs2CO3 as base under mild conditions. The protocol employs stable and easy to handle coupling partners, and is endowed with good substrate compatibility, leading to functional benzyl sulfones in good yields.