778641-02-4

Basic information

• Product Name: 1-BROMO-2-(4-BROMOPHENYL)ETHYLENE
• Synonyms: (E)-1-Bromo-2-(4-bromophenyl)ethylene;(E)-1-Bromo-4-(2-bromovinyl)benzene;1-BroMo-4-(2-broMoethenyl)benzene;1-BroMo-2-(4-broMophenyl)ethylene (contains cis isoMer);1-BROMO-2-(4-BROMOPHENYL)ETHYLENE
• CAS NO: 778641-02-4
• Molecular Formula: C₈H₆Br₂
• Molecular Weight: 261.94
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 778641-02-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 50-52°C
• Boiling Point: 284.436°C at 760 mmHg
• Flash Point: 142.922°C
• Appearance: /
• Density: 1.828g/cm³
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: 1.661
• Storage Temp.: -20°C Freezer
• Solubility: Acetone, Chloroform, DMSO, Ethyl Acetate, Methanol
• CAS DataBase Reference: 1-BROMO-2-(4-BROMOPHENYL)ETHYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-2-(4-BROMOPHENYL)ETHYLENE(778641-02-4)
• EPA Substance Registry System: 1-BROMO-2-(4-BROMOPHENYL)ETHYLENE(778641-02-4)

Safety Data

• Hazardous Substances Data: 778641-02-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

InChI:InChI=1/C8H6Br2/c9-6-5-7-1-3-8(10)4-2-7/h1-6H/b6-5+

Upstream product

• 139005-22-4 4-bromo-(3-carboxyl-3-oxoprop-1-enyl)benzene 
• 112595-55-8 (2RS,3SR)-2,3-dibromo-3-(4-bromophenyl)propanoic acid 
• 7732-18-5 water 
• 1122-91-4 4-bromo-benzaldehyde 
• 1200-07-3 3-(4-bromophenyl)acrylic acid 
• 136350-66-8 1-bromo-4-(2,2-dibromovinyl)benzene 

Downstream Products

• 32507-44-1 (E)-1-(buta-1,3-dien-1-yl)-4-bromobenzene 
• 349647-31-0 1-Bromo-4-((E)-2-phenoxy-vinyl)-benzene 
• 1379825-86-1 3-(4-bromophenyl)-1-phenyl-1H-indole 
• 13667-12-4 1-bromo-4-phenylethynylbenzene 
• 27549-93-5 (E)-3-(4-bromophenyl)acrylonitrile 
• 115665-77-5 (Z)-1-[2-bromovinyl]-4-bromobenzene 
• 115665-68-4 (E)-1-bromo-4-(2-bromovinyl)benzene 
• 6939-97-5 9-(4-bromobenzylidene)-9H-fluorene 

Relevant articles and documents

Selective Rhodium-Catalyzed Hydroformylation of Terminal Arylalkynes and Conjugated Enynes to (Poly)enals Enabled by a π-Acceptor Biphosphoramidite Ligand

The hydroformylation of terminal arylalkynes and enynes offers a straightforward synthetic route to the valuable (poly)enals. However, the hydroformylation of terminal alkynes has remained a long-standing challenge. Herein, an efficient and selective Rh-catalyzed hydroformylation of terminal arylalkynes and conjugated enynes has been achieved by using a new stable biphosphoramidite ligand with strong π-acceptor capacity, which affords various important E-(poly)enals in good yields with excellent chemo- and regioselectivity at low temperatures and low syngas pressures.

Iron-Catalyzed Reductive Vinylation of Tertiary Alkyl Oxalates with Activated Vinyl Halides

We present herein a rare and efficient method for the creation of vinylated all carbon quaternary centers via Fe-catalyzed cross-electrophile coupling of vinyl halides with tertiary alkyl methyl oxalates. The reaction displays excellent functional group tolerance and broad substrate scope, which allows cascade radical cyclization and vinylation to afford complex bicyclic and spiral structural motifs. The reaction proceeds via tertiary alkyl radicals, and the putative vinyl-Br/Fe complexation appears to be crucial for activating the alkene and enabling a possibly concerted radical addition/C-Fe forming process.

Pd-Catalyzed C(sp3)-C(sp2) cross-coupling of Y(CH2SiMe3)3(THF)2 with vinyl bromides and triflates

Pd-Catalyzed C(sp3)-C(sp2) cross-coupling of Y(CH2SiMe3)3(THF)2 with vinyl bromides and triflates has been developed for efficient synthesis of various allyltrimethylsilanes. The cross-coupling reaction was conducted at room temperature with low catalyst loading of either Pd(PPh3)4 or Pd(PPh3)2Cl2, and exhibited high efficiency and a broad substrate scope. In combination with the cross-coupling by the Lewis-acid catalyzed Hosomi-Sakurai reaction, a novel three-component one-pot cascade reaction was then accomplished to deliver homoallylic alcohols and ethers with high regioselectivity and diastereoselectivity. The three-component reaction defined the yttrium complex as a novel one-carbon synthon, which could either trigger bifunctionalization of alkenes or link two electrophiles and would find applications in organic synthesis.