77900-32-4

Basic information

• Product Name: 2H-Pyran-2-one, 6-[(1E)-2-(2,4-dimethoxyphenyl)ethenyl]-4-methoxy-
• CAS NO: 77900-32-4
• Molecular Formula: C16H16O5
• Molecular Weight: 288.3
• Mol File: 77900-32-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-Pyran-2-one, 6-[(1E)-2-(2,4-dimethoxyphenyl)ethenyl]-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyran-2-one, 6-[(1E)-2-(2,4-dimethoxyphenyl)ethenyl]-4-methoxy-(77900-32-4)
• EPA Substance Registry System: 2H-Pyran-2-one, 6-[(1E)-2-(2,4-dimethoxyphenyl)ethenyl]-4-methoxy-(77900-32-4)

Safety Data

• Hazardous Substances Data: 77900-32-4(Hazardous Substances Data)

Upstream product

• 1334928-11-8 4-methoxy-6-vinyl-2H-pyran-2-one 
• 7438-18-8 2,4-dimethoxybenzenediazonium tetrafluoroborate 
• 771-03-9 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 
• 56070-85-0 4-methoxy-2-oxo-2H-pyran-6-carboxaldehyde 
• 672-89-9 4-methoxy-6-methyl-2H-pyran-2-one 
• 675-10-5 4-hydroxy-6-methyl-2-pyron 

Relevant articles and documents

Heck-matsuda arylation as a strategy to access kavalactones isolated from polygala sabulosa, piper methysticum, and analogues

Herein, we describe the total syntheses of three bioactive pyrones isolated from Polygala sabulosa (i.e., 1, 4, and 7) and eight isolated from Piper methysticum (i.e., 8-10, 13, 15, and 18-20) using the Heck-Matsuda arylation as the key strategy. The evaluation of this methodology by employing different arenediazonium tetrafluoroborates revealed that the Heck arylation was more efficient when the olefin undergoing arylation possessed the vinyl-2-pyrone structural unit instead of the vinyl dihydro-2-pyrone moiety. The Heck-Matsuda arylation of many of the examined olefins proceeded in a practical manner with total regio- and stereocontrol.