779206-51-8Relevant articles and documents
Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use
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Paragraph 2152, (2019/03/30)
The invention discloses compounds of Formula (I), wherein A1, R1, R2, R3, R4, and n are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.
Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases
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Paragraph 1122; 1529; 1578, (2015/09/22)
The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.
TRIAZOLOTRIAZINES AS KINASE INHIBITORS
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Page/Page column 18-19, (2008/06/13)
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