77929-43-2

Basic information

• Product Name: 3-(2-Methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-5-trichloromethyl-1H-pyrrole-2-carboxylic acid benzyl ester
• Synonyms: 3-(2-Methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-5-trichloromethyl-1H-pyrrole-2-carboxylic acid benzyl ester
• CAS NO: 77929-43-2
• Molecular Weight: 476.741
• Mol File: 77929-43-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(2-Methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-5-trichloromethyl-1H-pyrrole-2-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-5-trichloromethyl-1H-pyrrole-2-carboxylic acid benzyl ester(77929-43-2)
• EPA Substance Registry System: 3-(2-Methoxycarbonyl-ethyl)-4-methoxycarbonylmethyl-5-trichloromethyl-1H-pyrrole-2-carboxylic acid benzyl ester(77929-43-2)

Safety Data

• Hazardous Substances Data: 77929-43-2(Hazardous Substances Data)

Upstream product

• 50622-64-5 benzyl 3-(2-methoxycarbonylethyl)-4-methoxycarbonylmethyl-5-methylpyrrole-2-carboxylate 

Downstream Products

• 55305-15-2 3,3'-bis-(2-methoxycarbonyl-ethyl)-4,4'-bis-methoxycarbonylmethyl-1H,1'H-5,5'-methanediyl-bis-pyrrole-2-carboxylic acid dibenzyl ester 
• 206861-06-5 C₃₄H₃₇Cl₃N₂O₁₂ 
• 111807-55-7 2,2,2-trichloroethyl 5-benzyloxycarbonyl-4-(2-methoxycarbonylethyl)-3-methoxycarbonylmethylpyrrole-2-carboxylate 
• 72423-57-5 5-benzyloxycarbonyl-4-(2-methoxycarbonylethyl)-3methoxycarbonylmethylpyrrole-2-carboxylic acid 

Relevant articles and documents

New method for the synthesis of pyrromethanes

Coupling reaction of 2-mercaptobenzothiazolylmethylpyrrole with α-free pyrrole in the presence of silver(I) triflate proceeds smoothly at room temperature to give a pyrromethane in excellent yield. The azafulvenium ion, an active form that reacts with α-f

SYNTHESIS OF UROPORPHYRIN-III, AND RELATED HEPTA- AND PENTA-CARBOXYLIC PORPHYRINS BY MODIFICATIONS OF THE MACDONALD METHOD

A modification of the MacDonald route has been developed in which all four pyrrole units of uroporphyrin-III have been derived from the same conveniently prepared starting pyrrole.Related hepta- and penta-carboxylic porphyrins have also been synthesised by condensation of appropriate α-formyl pyrromethane-α'-carboxylic acids; in each case other porphyrins with different numbers of acidic side-chains were also produced but the desired products were easily separated (as their methyl esters) by h.p.l.c.