77988-85-3

Basic information

• Product Name: Benzenecarboximidoyl chloride, N-[2-(3,4-dimethoxyphenyl)ethyl]-
• CAS NO: 77988-85-3
• Molecular Formula: C17H18ClNO2
• Molecular Weight: 303.788
• Mol File: 77988-85-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenecarboximidoyl chloride, N-[2-(3,4-dimethoxyphenyl)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarboximidoyl chloride, N-[2-(3,4-dimethoxyphenyl)ethyl]-(77988-85-3)
• EPA Substance Registry System: Benzenecarboximidoyl chloride, N-[2-(3,4-dimethoxyphenyl)ethyl]-(77988-85-3)

Safety Data

• Hazardous Substances Data: 77988-85-3(Hazardous Substances Data)

Upstream product

• 67616-16-4 N-[2-(3,4-dimethoxyphenyl)ethyl]benzamide 

Downstream Products

• 10172-51-7 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline 

Relevant articles and documents

The mechanism of the Bischler-Napieralski Reaction

The Bischler-Napieralski dihydroisoquinoline synthesis was proven to occur via imidoyl chlorides and the corresponding nitrilium salt.Two-step process required much milder conditions (20 degC - 50 degC) compared to drastic classical conditions of refluxing at 100 degC - 200 degC.The Bischler-Napieralski reaction is shown to share a common intermediate with two other well-known reactions: the von Braun and the Ritter reactions