78075-71-5

Basic information

• Product Name: (4R,αS)-N(1)-(α-methylbenzyl)-4-phenylazetidin-2-one
• Synonyms: (4R,αS)-N(1)-(α-methylbenzyl)-4-phenylazetidin-2-one
• CAS NO: 78075-71-5
• Molecular Weight: 251.328
• Mol File: 78075-71-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (4R,αS)-N(1)-(α-methylbenzyl)-4-phenylazetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,αS)-N(1)-(α-methylbenzyl)-4-phenylazetidin-2-one(78075-71-5)
• EPA Substance Registry System: (4R,αS)-N(1)-(α-methylbenzyl)-4-phenylazetidin-2-one(78075-71-5)

Safety Data

• Hazardous Substances Data: 78075-71-5(Hazardous Substances Data)

Upstream product

• 265669-72-5 tert-butyl (3R,αS)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate 
• 146937-36-2 tert-butyl (3R,αS)-3-[N-(α-methylbenzyl)amino]-3-phenylpropanoate 
• 17480-69-2 (S)-N-benzyl-1-phenylethylamine 
• 14990-09-1 tert-butyl cinnamate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 100-52-7 benzaldehyde 
• 127-19-5 N,N-dimethyl acetamide 
• 3129-98-4 (S)-N-benzylidene(1-phenylethylamine) 
• 618-42-8 1-piperidin-1-yl-ethanone 

Relevant articles and documents

Solvent-free stereoselective synthesis of β-aryl-β-amino acid esters by the Rodionov reaction using microwave irradiation

A rapid method for the title synthesis of β-aryl-β-amino acid esters was developed, and the absolute configurations of newly formed C-3 chiral centres in the major and minor diastereomers of the resulting ethyl N-[(S)-α-methylbenzyl]-β-amino-β-phenyl-propionate were determined.

Lithium (α-Methylbenzyl)allylamide: A Differentially Protected Chiral Ammonia Equivalent for the Asymmetric Synthesis of β-Amino Acids and β-Lactams

The addition products from the highly stereoselective conjugate additions of lithium (αS)-(α-methylbenzyl)allylamide to α,β-unsaturated tert-butyl esters are efficiently deallylated with tris(triphenylphosphine)rhodium(I) chloride and converted, after tra