78178-72-0

Basic information

• Product Name: 4'-benzyloxy-2-pyrrolidin-2-ylacetophenone
• Synonyms: 4'-benzyloxy-2-pyrrolidin-2-ylacetophenone
• CAS NO: 78178-72-0
• Molecular Weight: 295.381
• Mol File: 78178-72-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4'-benzyloxy-2-pyrrolidin-2-ylacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-benzyloxy-2-pyrrolidin-2-ylacetophenone(78178-72-0)
• EPA Substance Registry System: 4'-benzyloxy-2-pyrrolidin-2-ylacetophenone(78178-72-0)

Safety Data

• Hazardous Substances Data: 78178-72-0(Hazardous Substances Data)

Upstream product

• 53090-45-2 ethyl 3-[4-(benzyloxy)phenyl]-3-oxopropanoate 
• 78178-57-1 3-(4-(benzyloxy)phenyl)-3-oxopropanoic acid 
• 5724-81-2 1-pyrroline 

Downstream Products

• 62024-32-2 1-(4-hydroxyphenyl)-2-(2-pyrrolidinyl)ethanone 

Relevant articles and documents

Synthesis, in vitro and in vivo cytotoxicity of 6,7-diaryl-2,3,8,8a-tetrahydroindolizin-5(1H)-ones

A 6,7-diaryl-2,3,8,8a-tetrahydroindolizin-5(1H)-one library was constructed and tested against the colon cancer cell line HCT-116 as an initial screen for cytotoxic properties. Of this library, the parent compound, in which the southern aromatic ring remains unsubstituted, and the northern aromatic ring carries a 4-methoxy group, exhibited the most potent cytotoxicity with an IC50 value of 0.39 μM and displayed promising activity in vivo in the NCI's mouse hollow fiber assay.