78185-64-5 Usage
Description
Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside is a chemical compound derived from ribofuranoside, a type of sugar. It features a complex molecular structure with toluoyl groups added to the sugar molecule, enhancing its stability and ease of manipulation in laboratory settings. Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside is valuable for various scientific applications, including the development of new drugs and the study of carbohydrate chemistry and biochemistry.
Uses
Used in Organic Synthesis:
Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside is used as an intermediate in organic synthesis for the creation of complex organic molecules. Its stability and reactivity make it a useful building block in the synthesis of pharmaceuticals and other organic compounds.
Used in Research:
In the field of research, Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside is utilized for studying carbohydrate chemistry and biochemistry. Its unique structure allows scientists to explore the interactions and properties of sugars in biological systems, contributing to a deeper understanding of carbohydrate-related processes.
Used in Drug Development:
Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside is employed in the development of new drugs, particularly those targeting carbohydrate-related diseases or conditions. Its precise structure and properties make it a valuable tool for designing and testing potential therapeutic agents.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside is used as a key component in the synthesis of certain drugs. Its stability and reactivity contribute to the production of effective and reliable pharmaceutical products.
Used in Academic Research:
Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside is utilized in academic research settings to advance the understanding of carbohydrate chemistry and its role in biological processes. Methyl 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribo-furanoside serves as a valuable research tool for scientists and researchers in universities and research institutions.
Check Digit Verification of cas no
The CAS Registry Mumber 78185-64-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,1,8 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 78185-64:
(7*7)+(6*8)+(5*1)+(4*8)+(3*5)+(2*6)+(1*4)=165
165 % 10 = 5
So 78185-64-5 is a valid CAS Registry Number.
78185-64-5Relevant articles and documents
Preparation of pyridine-stretched 2′-deoxyhypoxanthosine phosphoramidite
Clayton, Russell,Davis, Michael L.,Li, Wei,Fraser, William,Ramsden, Christopher A.
, p. 87 - 104 (2017/06/19)
Pyridine-stretched 2-deoxyhypoxanthosine (strH) phosphoramidite was prepared in eight steps from Hoffer's sugar (2-deoxy-3,5-di-O-(p-toluoyl)-a-D-erythro-pentofuranosyl chloride). Improved synthesis of the Hoffer sugar was achieved without need for distillation or chromatographic separation of intermediates, or use of gaseous HCl. Conditions were optimised to provide a key nitrile intermediate for the preparation of strH whereby the cesium salt of 4(5)-nitroimidazole was glycosylated using Hoffer's sugar. The nitrile intermediate was also used to prepare pyridine-stretched 2-deoxyadenosine (strA) and pyridine-stretched 2-deoxy-2,6-diaminonebulamine (strD). Preliminary studies indicate that strH forms a stronger, size-expanded base pair with adenine compared with the Watson-Crick thymine-adenine base pair.
Improved Syntheses of Halofuranose Derivatives with the Desired α-Configuration
Chin, Tsung-Mei,Huang, Liang-Kuen,Kan, Lou-Sing
, p. 413 - 416 (2007/10/03)
Chlorination of ribofuranose or 2-deoxyribofuranose derivatives was carried out in a 1,4-dioxane solution of hydrogen chloride. This improved procedure allowed the syntheses of 1-chloro-α-D-ribofuranose and 1-chloro-2-deoxy-α-D-ribofuranose derivatives and offered ease of handling, high yield, and the stereo-controlled α-configuration at C-1.