782-77-4

Basic information

• Product Name: 2-([(4-CHLOROPHENYL)IMINO]METHYL)PHENOL
• Synonyms: 2-([(4-CHLOROPHENYL)IMINO]METHYL)PHENOL;Phenol,2-(((4-chlorophenyl)imino)methyl)-;N-(2-Hydroxybenzylidene)-4-chloroaniline;N-(4-Chlorophenyl)-2-hydroxybenzenemethanimine
• CAS NO: 782-77-4
• Molecular Formula: C₁₃H₁₀ClNO
• Molecular Weight: 231.68
• Mol File: 782-77-4.mol
• Article Data: 52

Chemical Properties

• Boiling Point: 376.9°C at 760 mmHg
• Flash Point: 181.7°C
• Appearance: /
• Density: 1.395g/cm³
• Vapor Pressure: 7.02E-06mmHg at 25°C
• Refractive Index: 1.745
• CAS DataBase Reference: 2-([(4-CHLOROPHENYL)IMINO]METHYL)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-([(4-CHLOROPHENYL)IMINO]METHYL)PHENOL(782-77-4)
• EPA Substance Registry System: 2-([(4-CHLOROPHENYL)IMINO]METHYL)PHENOL(782-77-4)

Safety Data

• Hazardous Substances Data: 782-77-4(Hazardous Substances Data)

Usage

General Description

2-([(4-Chlorophenyl)imino]methyl)phenol is a chemical compound with the molecular formula C13H10ClNO. It is an organic compound that belongs to the class of phenols and derivatives. This chemical is a member of the class of compounds known as salicylanilides and derivatives. It has a molecular weight of 229.68 g/mol and a melting point of 153-157°C. The compound is primarily used in the manufacturing of pharmaceutical products and is also used as an intermediate in organic synthesis. It is important to handle this compound with care as it is a potential toxic substance.

InChI:InChI=1/C13H10ClNO/c14-11-5-7-12(8-6-11)15-9-10-3-1-2-4-13(10)16/h1-9,15H

Upstream product

• 106-47-8 4-chloro-aniline 
• 90-02-8 salicylaldehyde 
• 19865-61-3 N-(salicylidene)-4-chlorophenylamine-N-oxide 
• 89-95-2 2-methyl-benzyl alcohol 
• 53745-07-6 6-[1-(4-Chloro-phenylamino)-meth-(Z)-ylidene]-cyclohexa-2,4-dienone 

Downstream Products

• 33877-81-5 3-(4-chloro-phenyl)-3,4-dihydro-2H-benzo[e][1,3,2]oxazaborinine 
• 81824-94-4 3-(4-Chloro-phenyl)-2-[(E)-2-(2-hydroxy-phenyl)-vinyl]-3H-quinazolin-4-one 
• 7193-94-4 2-((4-chlorophenylamino)methyl)phenol 
• 127142-98-7 1-(4-Chloro-phenyl)-2-(2-hydroxy-phenyl)-4-(4-methoxy-phenyl)-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 126884-71-7 (4-Chloro-phenyl)-(2,3-dihydro-benzofuran-3-yl)-amine 
• 89-95-2 2-methyl-benzyl alcohol 
• 51892-07-0 3-(4-chlorophenyl)-3,4-dihydro-2H-benzo[e][1,3]oxazine 
• 116334-59-9 bis(N-(p-chlorophenyl)salicylaldiminato)(1,10-phenanthroline)zinc(II) 
• 16985-34-5 bis(2-{(E)-[(4-chlorophenyl)imino]methyl}phenolate)zinc(II) 
• 32065-25-1 bis{N-(4-chlorophenyl)salicylideneaminato}oxovanadium(IV) 
• 28548-10-9 {PbCl₂(C₁₃H₉ClNO)2} 
• 108151-43-5 tris(salicylidene-4-chloro-anilinato)-cobalt(III) 
• 97982-50-8 C₆H₅AsO₃^(2-)*Al⁽³⁺⁾*C₆H₄ClNCHC₆H₄O^(1-) = C₆H₅AsO₃Al(OC₆H₄CHNC₆H₄Cl) 

Relevant articles and documents

Structure and characterization of bis(N-p-chloro-phenyl-salicylideneaminate) Schiff base copper(II) complex: Cu[N-p-Cl-Ph-Sal]2

The crystal and molecular structure of the title compound has been determined by X-ray crystallography. It crystallizes in the monoclinic system, space group P21/c, with lattice parameters a = 13.678(3), b = 10.729(2), c = 8.1996(2) A, β= 98.96°, V = 1188.7(4) A 3, and Z = 4. The crystal structure contains two centrosymmetric molecules of bis (N-p-chloro-phenyl-salicylideneaminate) Schiff base copper(II). Copper(II) ion is coordinated in a slightly distorted trans square-planar configuration, the distortion consisting of a reduction of the N-Cu-O angle with the chelate rings from the ideal value of 90°. The p-chlorophenyl rings with salicylidene moieties form a dihedral angle of 38.96°.

Facile synthesis, solublization studies and anti-inflammatory activity of amorphous zinc(Ii) centered aldimine complexes

In this study, Zn(II) centered complexes with aldimine derivatives were synthesized using green solvent, polyethylene glycol (PEG-400) and amorphous complexes were characterized by FT-IR, multinuclear (1H and13C NMR), elemental and thermal analysis. Thermogravimetric analysis indicated the extended thermal stability of the synthesized complexes. All the Zn(II) complexes show very significant photoexcitation in the range of 318 – 384 nm and photoemission in the range of 502 – 562 nm. Among all the complexes, Zn(II) complex (3Zn) showed minimum band gap value, 2.35 eV. These amorphous complexes have been reported for their wide applications in biomedical sciences. The synthesized aldimine ligands and Zn(II) complexes were investigated for anti-inflammatory activity and these complexes showed more anti-inflammatory potential than the corresponding aldimine ligands. The solubilization of zinc complexes in sodium dodecyl sulphate was also investigated to reveal the interaction of metal complexes by using UV-Visible spectroscopy and electrical conductivity measurements.

Ru(III) complexes of phenoxy-imine ligands: Synthesis, characterisation and testing as oxidation catalysts

Summary: A series of new mononuclear Ru(III) complexes bearing phenoxy-imine Schiff base tetradentate ligands (phenylimino, 4-chlore phenylimino, 3,4-dichlore phenylimino) have been prepared and characterized by elemental analysis, TGA, UV-VIS, FT-IR, 1H-NMR and 13C NMR spectra. The proposed structure of the ligands have a O2N2 core to form mononuclear Ru (III) complexes. Preliminary studies on the catalytic performances of the compounds in the cycloalkane oxydation are described. The catalytic effect of all Ru complexes results in the epoxidation reaction of cyclohexane, as shown in the substrate conversion reaction appears to be very high.

Effect of substituents on the UV spectra of supermolecular system: Silver nanoparticles with bi-aryl Schiff bases containing hydroxyl

Effect of substituents on the ultraviolet (UV) spectra of supermolecular system involving silver nanoparticles (AgNPs) and Schiff bases was investigated. AgNPs and 49 samples of model compounds (MC), bi-aryl Schiff bases containing hydroxyl (XBAY, involving 4-OHArCH?NArY, 2-OHArCH?NArY, XArCH?NAr-4′-OH, and XArCH?NAr-2′-OH), were synthesized. The size of AgNPs was characterized by transmission electron microscopy (TEM), and the UV absorption spectra of AgNPs, XBAYs, and MC-AgNPs mixed solutions were measured, respectively. The results show that (1) the size of AgNPs is larger in MC-AgNPs solutions than that in AgNPs solution due to the distribution of MC molecules on the surface of AgNPs; (2) the UV absorption wavelength of XBAYs changes in the action of AgNPs and their wavelength shift exists limitation between XBAY and MC-AgNPs solutions; and (3) the wavelength shift limit of MC-AgNPs (λWSL) is influenced by the substituents X and Y and the position of hydroxyl OH. The wavenumber ΔνWSL of λWSL can be quantified by employing the excited-state substituent constant σexCC and Hammett constant σ of substituents X and Y. Comparing with the 4-OH, the 4′-OH makes the ΔνWSL a red shift, whereas the 2′-OH, comparing with the 2-OH, makes the ΔνWSL a blue shift.