78227-85-7

Basic information

• Product Name: 2,4-bis(methylsulfanyl)-1-nitrobenzene
• Synonyms: 2,4-bis(methylsulfanyl)-1-nitrobenzene
• CAS NO: 78227-85-7
• Molecular Formula: C₈H₉NO₂S₂
• Molecular Weight: 215.29256
• Mol File: 78227-85-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,4-bis(methylsulfanyl)-1-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-bis(methylsulfanyl)-1-nitrobenzene(78227-85-7)
• EPA Substance Registry System: 2,4-bis(methylsulfanyl)-1-nitrobenzene(78227-85-7)

Safety Data

• Hazardous Substances Data: 78227-85-7(Hazardous Substances Data)

Usage

General Description

2,4-bis(methylsulfanyl)-1-nitrobenzene is a chemical compound with the molecular formula C8H10N2O2S2. It is commonly used as an intermediate in the synthesis of various organic compounds and is primarily employed in the production of dyes, pharmaceuticals, and agricultural chemicals. 2,4-bis(methylsulfanyl)-1-nitrobenzene is a yellow crystalline solid with a distinct odor, and it is considered to be toxic if ingested or inhaled. Its primary use is as a precursor in the production of other chemicals, and it is handled with appropriate safety precautions due to its potential health hazards. Additionally, it is known by other names such as 1,5-dimercapto-2,4-dinitrobenzene and p-(methylthio)nitrobenzene. Overall, 2,4-bis(methylsulfanyl)-1-nitrobenzene is a versatile industrial chemical with a range of important applications in various industries.

Upstream product

• 611-06-3 2,4-dichloronitrobenzene 
• 5188-07-8 sodium thiomethoxide 
• 2388-69-4 1,3-bis(methylthio)benzene 
• 857785-91-2 bis-(3-methylsulfanyl-4-nitro-phenyl)-disulfide 
• 67-68-5 dimethyl sulfoxide 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 446-35-5 2,4-Difluoronitrobenzene 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 626-04-0 3-mercaptothiophenol 
• 121-47-1 3-aminobenzenesulfonic acid 
• 70019-41-9 4-chloro-2-(methylthio)-1-nitrobenzene 
• 1189038-13-8 2,4-bis(phenylseleno)nitrobenzene 

Downstream Products

• 78228-03-2 2,4-bis-methanesulfonyl-1-nitro-benzene 
• 42986-91-4 2,4-di-(methylsulfonyl)-aniline 

Relevant articles and documents

Ionic Reactivity of 2-Isocyanoaryl Thioethers: Access to 2-Halo and 2-Aminobenzothia/Selenazoles

An ionic cascade insertion/cyclization reaction of thia-/selena-functionalized arylisocyanides has been successfully developed for the efficient and practical synthesis of 2-halobenzothiazole/benzoselenazole derivatives. This synthetic protocol, incorporating a halogen atom when forming the five-membered ring of benzothia/selenazoles, is different from the existing ones, where halogenation of the preformed benzothia/selenazole precursors happens. Additionally, a facile access to 2-aminobenzothiazoles is also achieved by the one-pot cascade reaction of 2-isocyanoaryl thioethers, iodine, and amines.

THE THIOLATE ANION AS A NUCLEOPHILE PART X. REACTIONS OF SOME NITROFLUOROAROMATICS

The reactions of various nitrofluorobenzenes, C6HxFyNO2, with sodium methanethiolate have been studied in ethylene glycol/pyridine mixture as solvent.All the fluorine atoms, but not the nitrogroups, could be substituted by the methylthio group.The reactions have also been studied with the addition of a deactivating group, either methyl or amino, on the aromatic nucleus.Some of the methylthio groups in the products were oxidized to the corresponding sulfones.The new compounds isolated have been characterized and their spectra (IR, NMR and mass) examined.