78246-90-9

Basic information

• Product Name: Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethyl-
• Synonyms: Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl- (9CI)
• CAS NO: 78246-90-9
• Molecular Formula: C9H9 Cl2 F3 O
• Molecular Weight: 261.071
• Mol File: 78246-90-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethyl-(78246-90-9)
• EPA Substance Registry System: Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethyl-(78246-90-9)

Safety Data

• Hazardous Substances Data: 78246-90-9(Hazardous Substances Data)

Usage

General Description

Cyclopropanecarbonylchloride, 3-(2-chloro-3,3,3-trifluoro-1-propen-1-yl)-2,2-dimethyl- is a chemical compound characterized by its cyclopropane and carbonyl chloride groups, as well as the presence of a 2-chloro-3,3,3-trifluoro-1-propen-1-yl moiety and 2,2-dimethyl substituents. It is commonly used in organic synthesis to introduce the cyclopropane ring and the carbonyl chloride functional group into various compounds. This chemical may also have applications in the pharmaceutical and agrochemical industries due to its unique structural features and potential reactivity. Additionally, it is important to handle this compound with care, as its reactivity and potential hazards should be considered when working with it in a laboratory setting.

Upstream product

• 74609-46-4 3-(2-chloro-3,3,3-trifluoroprop-1-en-yl)-2,2-dimethylcyclopropanecarboxylic acid 

Downstream Products

• 82657-04-3 rel-(1R,3R)-(2-methyl[1,1'-biphenyl]-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]-2,2-dimethylcyclopropanecarboxylate 
• 68085-85-8 α-cyano-3-phenoxybenzyl-3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarboxylate 
• 1581244-68-9 C₁₇H₁₃ClF₈O₂ 

Relevant articles and documents

NOVEL CRYSTALLINE FORM OF TEFLUTHRIN, PROCESS FOR ITS PREPARATION AND USE THEREOF

Provided are the crystalline form of tefluthrin of formula (I), the crystal preparation process, the analyses of the crystal through various analytical methods and using the crystal to prepare stable agrochemical formulation. Also provided is the use of various solvents towards the crystalline form preparation conditions.

Synthesis and evaluation of a new series of substituted acyl(thio)urea and thiadiazolo [2,3-a] pyrimidine derivatives as potent inhibitors of influenza virus neuraminidase

A series of substituted acyl(thio)urea and 2H-1,2,4-thiadiazolo [2,3-a] pyrimidine derivatives were prepared and both of their cell culture and enzymatic activity toward influenza virus were tested. Their in vitro neuraminidase inhibitory activities were in good agreement with the corresponding activities in cultured cells and they were evaluated as potent neuraminidase inhibitors. Of the analogues that demonstrated IC50s 0.1 μM, 16 and 60 were further investigated as candidates with the most potential for future development. The molecular docking work of the representative compound was described to provide more insight into their mechanism of action and further rationalize the observations of this new series herein, which represents a novel class of highly potent and selective inhibitors of influenza virus.