782501-09-1

Basic information

• Product Name: dichloro(3,5-di-tert-butyl-4-methoxyphenyl)phosphine
• Synonyms: dichloro(3,5-di-tert-butyl-4-methoxyphenyl)phosphine
• CAS NO: 782501-09-1
• Molecular Weight: 321.227
• Mol File: 782501-09-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dichloro(3,5-di-tert-butyl-4-methoxyphenyl)phosphine(CAS DataBase Reference)
• NIST Chemistry Reference: dichloro(3,5-di-tert-butyl-4-methoxyphenyl)phosphine(782501-09-1)
• EPA Substance Registry System: dichloro(3,5-di-tert-butyl-4-methoxyphenyl)phosphine(782501-09-1)

Safety Data

• Hazardous Substances Data: 782501-09-1(Hazardous Substances Data)

Upstream product

• 1516-96-7 4-bromo-2,6-di-tert-butylanisole 

Downstream Products

• 782501-07-9 3,5-di-tert-butyl-4-methoxyphenylphosphine 

Relevant articles and documents

Synthesis of β-Lactams by Palladium(0)-Catalyzed C(sp3)?H Carbamoylation

A general and user-friendly synthesis of β-lactams is reported that makes use of Pd0-catalyzed carbamoylation of C(sp3)?H bonds, and operates under stoichiometric carbon monoxide in a two-chamber reactor. This reaction is compatible with a range of primary, secondary and activated tertiary C?H bonds, in contrast to previous methods based on C(sp3)?H activation. In addition, the feasibility of an enantioselective version using a chiral phosphonite ligand is demonstrated. Finally, this method can be employed to synthesize valuable enantiopure free β-lactams and β-amino acids.