78315-33-0

Basic information

• Product Name: 1-(2,2-Difluoro-vinyl)-cyclohexanol
• Synonyms: 1-(2,2-Difluoro-vinyl)-cyclohexanol
• CAS NO: 78315-33-0
• Molecular Weight: 162.179
• Mol File: 78315-33-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(2,2-Difluoro-vinyl)-cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,2-Difluoro-vinyl)-cyclohexanol(78315-33-0)
• EPA Substance Registry System: 1-(2,2-Difluoro-vinyl)-cyclohexanol(78315-33-0)

Safety Data

• Hazardous Substances Data: 78315-33-0(Hazardous Substances Data)

Upstream product

• 75-38-7 Vinylidene fluoride 
• 108-94-1 cyclohexanone 
• 78315-30-7 2,2-difluoro vinyllithium 

Downstream Products

• 167385-09-3 1-Bromo-2-cyclohexylidene-1,1-difluoroethane 
• 40203-74-5 methyl 2-cyclohexylideneacetate 

Relevant articles and documents

Stereoselective synthesis of 1-bromo-(or 1-chloro-) 1,1-difluoro-2-alkenes

A highly regio- and stereo-selective method for the introduction of a bromo- (or chloro-) difluoromethylene group into various unsaturated systems is described. The key step is the treatment of 1,1-difluoro-1-alken-3-ols with thionyl bromide (or chloride).

Straightforward synthesis of α,β-unsaturated acids and derivatives

A general C2 vinylic homologation from carbonyl compounds (aldehydes or ketones) which leads to various α,β-insaturated acids, esters and amides, is described.

Reaction de CF2=CH2 avec les organolithiens . Une nouvelle preparation du difluorovinyllithium

2,2-Difluorovinyllithium has been prepared in quantitative yield from CF2=CH2 and sec.butyllithium at low temperature.Reaction of 2,2-difluorovinyllithium with carbonyl groups gives the corresponding alcohols.