783349-41-7

Basic information

• Product Name: 3-Furancarboxylicacid,tetrahydro-2,2-dimethyl-5-oxo-,(3R)-(9CI)
• Synonyms: 3-Furancarboxylicacid,tetrahydro-2,2-dimethyl-5-oxo-,(3R)-(9CI)
• CAS NO: 783349-41-7
• Molecular Formula: C7H10O4
• Molecular Weight: 0
• Product Categories: CARBOXYLICACID
• Mol File: 783349-41-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Furancarboxylicacid,tetrahydro-2,2-dimethyl-5-oxo-,(3R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Furancarboxylicacid,tetrahydro-2,2-dimethyl-5-oxo-,(3R)-(9CI)(783349-41-7)
• EPA Substance Registry System: 3-Furancarboxylicacid,tetrahydro-2,2-dimethyl-5-oxo-,(3R)-(9CI)(783349-41-7)

Safety Data

• Hazardous Substances Data: 783349-41-7(Hazardous Substances Data)

Upstream product

• 38746-47-3 (R)-5,5-dimethyl-4-(3-oxo-butyl)-dihydro-furan-2-one 
• 79-91-4 terebic acid 
• 1187-69-5 (-)-(R)-2-isopropylbutane-1,4-dioic acid 
• 6934-77-6 β-carbomethoxy-γ,γ-dimethyl-γ-butyrolactone 
• 34566-25-1 ethyl 2,2-dimethyl-5-oxotetrahydro-3-furancarboxylate 

Relevant articles and documents

Beta-carbolines useful for treating inflammatory disease

This invention provides beta-carboline compounds of formula III-A-aa: wherein Q, G, R1, R2, R3, and R6b are as described in the specification. The compounds are useful for treating diseases such as inflammatory diseases and cancer.

Chemoenzymatic synthesis of enantioenriched 5-oxo-tetrahydro-3- furancarboxylic acid derivatives

(R)-(+)-Paraconic acid 4, (S)-(-)-terebic acid 6 and their corresponding methyl and ethyl esters having ee's ranging from 60% to 92% were obtained by enzymatic resolution of their racemates. The enzymatic resolution of racemic ethyl γ-methylparaconates 14a and 14b allowed the isolation of the unreacted ester (2R,3R)-(+)-14a and that of the lactonic acid (2S,3R)-(-)-5b with 80% and 93% ee, respectively, the former by the use of Horse liver acetone powder (HLAP), the latter using α-chymotrypsin (α-CT). The enantiomeric ethyl (2S,3S)-(-)-14a and (2S,3R)-(-)-14b, both with >99% ee, were obtained by baker's yeast reduction of diethyl acetylsuccinate.