78415-89-1

Basic information

• Product Name: Cyclobutane, (chloromethyl)-
• CAS NO: 78415-89-1
• Molecular Formula: C5H9Cl
• Molecular Weight: 104.579
• Mol File: 78415-89-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclobutane, (chloromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutane, (chloromethyl)-(78415-89-1)
• EPA Substance Registry System: Cyclobutane, (chloromethyl)-(78415-89-1)

Safety Data

• Hazardous Substances Data: 78415-89-1(Hazardous Substances Data)

Usage

General Description

Cyclobutane, (chloromethyl)- is a chemical compound with the molecular formula C5H9Cl. It is a chloromethyl derivative of cyclobutane, which is a cycloalkane with a four carbon ring. The chloromethyl group is a halogenated alkyl group, which means it contains a chlorine atom bonded to a carbon atom. Cyclobutane, (chloromethyl)- has potential applications in organic synthesis and pharmaceutical research due to its unique structural properties and reactivity. It is important to handle this chemical with caution and follow proper safety guidelines when working with it in a laboratory setting.

Upstream product

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Downstream Products

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• 747350-61-4 Cyclobutylmethyl-(3-methoxy-3,3-diphenyl-propyl)-amine 

Relevant articles and documents

The Kinetics and Mechanism of Ring Opening of Radicals containing the Cyclobutylcarbinyl System

The kinetic parameters of β-fission of radicals containing the cyclobutylcarbinyl system have been determined by analysis of the mixtures obtained when suitable chloro-compounds are treated with tributylstannane.Under these conditions ring opening is irreversible and in the rigid bicyclic system (4) is under stereoelectronic control.For ring opening of cyclobutylcarbinyl radical (8) kf = 4.3 x 103 s-1 at 60 deg C, and the best values of the activation parameters appear to be ΔH(excit.) = 12.2 kcal mol-1 and ΔS(excit.) = -7.4 cal mol-1 K-1.Monocyclic systems undergo preferential fission of the more substituted βγ-bond.Methyl substituents at the α-, β-, or δ-positions have little effect but γ-substitution strongly enhances the rate of ring opening.The transition state is reactant-like and has a similar disposition of centres to that (1) for homolytic addition.