78417-26-2

Basic information

• Product Name: 5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone
• Synonyms: 5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone;5,7-Dihydroxy-2-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-chromen-4-one
• CAS NO: 78417-26-2
• Molecular Formula: C18H16O8
• Molecular Weight: 360.31484
• Mol File: 78417-26-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 244-245℃ (chloroform ethanol )
• Boiling Point: 646.1±55.0 °C(Predicted)
• Appearance: /
• Density: 1.461±0.06 g/cm3(Predicted)
• PKA: 6.46±0.40(Predicted)
• CAS DataBase Reference: 5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone(78417-26-2)
• EPA Substance Registry System: 5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone(78417-26-2)

Safety Data

• Hazardous Substances Data: 78417-26-2(Hazardous Substances Data)

Usage

Description

5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone is a flavonoid compound found in the Artemisia species. It is characterized by its unique chemical structure, which includes three hydroxyl groups at the 5, 7, and 3' positions, and three methoxy groups at the 6, 4', and 5' positions. 5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone has attracted significant attention due to its potential chemopreventive properties and interaction with farnesyl protein transferase.

Uses

Used in Pharmaceutical Industry:
5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone is used as a chemopreventive agent for its potential to inhibit the development and progression of cancer. Its interaction with farnesyl protein transferase, an enzyme involved in the post-translational modification of proteins, suggests that it may play a role in disrupting cancer-related signaling pathways and preventing tumor growth.
Used in Cancer Research:
In the field of cancer research, 5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone is used as a compound of interest for further investigation into its potential as a therapeutic agent. Its chemopreventive activity and interaction with farnesyl protein transferase make it a promising candidate for the development of novel cancer treatments.
Used in Natural Products Industry:
5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone is also used in the natural products industry as a bioactive compound derived from the Artemisia species. Its potential health benefits and chemopreventive properties make it a valuable ingredient for the development of natural health products and supplements.