78429-24-0

Basic information

• Product Name: 8-Chloro-1-phenyl-octan-4-one
• Synonyms: 8-Chloro-1-phenyl-octan-4-one
• CAS NO: 78429-24-0
• Molecular Weight: 238.757
• Mol File: 78429-24-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 8-Chloro-1-phenyl-octan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Chloro-1-phenyl-octan-4-one(78429-24-0)
• EPA Substance Registry System: 8-Chloro-1-phenyl-octan-4-one(78429-24-0)

Safety Data

• Hazardous Substances Data: 78429-24-0(Hazardous Substances Data)

Upstream product

• 10297-05-9 1-chloro 4-iodobutane 
• 78427-99-3 2-(6-(2-methoxyethyl)pyridyl) 4-phenylbutanoate 
• 6940-78-9 4-chlorobutyl bromide 
• 177756-65-9 N-methoxy-N-methyl-4-phenylbutyramide 

Relevant articles and documents

Copper-catalyzed radical ring-opening halogenation with HX

An efficient copper-catalyzed radical ring-opening halogenation with HX (aq) is described. This protocol features redox-neutral conditions, green halogen sources, and a broad substrate scope, providing practical access to distally chlorinated, brominated and iodinated alkyl ketones and alkyl nitriles with moderate to good yields. This journal is

ANTIBACTERIAL QUINOLINE DERIVATIVES

The present invention relates to novel substituted quinoline derivatives according to the general Formula (Ia) or Formula (Ib): including any stereochemically isomeric form thereof, a pharmaceutically acceptable salt thereof, a N-oxide form thereof or a solvate thereof. The claimed compounds are useful for the treatment of a bacterial infection. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the claimed compounds, the use of the claimed compounds or compositions for the manufacture of a medicament for the treatment of a bacterial infection and a process for preparing the claimed compounds.

A CONVENIENT METHOD FOR THE DIRECT PREPARATION OF KETONES FROM 2-(6-(2-METHOXYETHYL)PYRIDYL) CARBOXYLATES AND ALKYL IODIDES BY USE OF ZINC DUST AND A CATALYTIC AMOUNT OF NICKEL DICHLORIDE

Treatment of 2-(6-(2-methoxyethyl)pyridyl) carboxylates with alkyl iodides in the presence of zinc dust and a catalytic amount of NiCl2 in DMF at 50 deg C affords unsymmetrical ketones in good yields by a one-pot procedure.